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Ultrasonography

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...

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Updated: May 5, 2026

Thermal Ablation for the Treatment of Abdominal Tumors

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

Microwave Ablation Monitoring Using Thermoacoustic and Ultrasound Tomography.

David C Garrett¹, Yousuf Aborahama¹, Jinhua Xu¹

¹Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125 USA.

IEEE Journal of Microwaves

|May 4, 2026

Summary

This study introduces a novel imaging technique using modulated microwave signals to monitor microwave ablation in real-time. This method allows for personalized treatment adjustments, improving tumor ablation and sparing healthy tissue.

Keywords:

Microwave ablation chirp modulation medical diagnostic imaging photoacoustic imaging ultrasonic imaging

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Published on: January 13, 2023

Area of Science:

Medical Imaging
Biomedical Engineering
Oncology

Background:

Microwave ablation is a minimally invasive technique for tumor destruction.
Clinical microwave ablation efficacy is limited by patient and tissue variations.
Personalized treatment parameters are needed for optimal outcomes.

Purpose of the Study:

To introduce an imaging technique for real-time monitoring of microwave ablation.
To enable adaptive control of microwave ablation procedures.
To improve lesion coverage and spare healthy tissue.

Main Methods:

Modulated microwave signals were employed, maintaining clinical power levels.
Thermoacoustic signals were generated by time-varying tissue heating.
Images of spatial heat deposition were reconstructed and combined with thermal models.
The approach was validated in ex vivo bovine liver against ultrasound tomography and dissection.

Main Results:

The technique successfully generated thermoacoustic signals for imaging heat deposition.
Spatial temperature profiles and ablation status were estimated over time.
Validation confirmed the accuracy of the imaging and estimation methods.

Conclusions:

The developed imaging technique enables closed-loop monitoring of microwave ablation.
Adaptive control of ablation procedures is feasible.
This approach has the potential to optimize therapeutic outcomes in clinical settings.