A large-scale 12-lead electrocardiogram dataset for acute coronary syndrome prediction containing 19,955 ECGs

Xinyue Du1, Ying Liu2, Lingli Wang1

  • 1Department of Cardiovascular Medicine, Cardiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Scientific Data
|May 4, 2026
PubMed

Insights

A new, large dataset of electrocardiograms (ECGs) for acute coronary syndrome (ACS) prediction is now available. This resource, along with a baseline AI model, aims to advance cardiovascular disease research and diagnosis.

Area of Science:

  • Cardiology
  • Artificial Intelligence
  • Medical Informatics

Background:

  • Acute coronary syndrome (ACS) is a critical manifestation of coronary heart disease, necessitating rapid diagnosis via electrocardiograms (ECGs).
  • Existing artificial intelligence (AI) models show promise but are hindered by limited, accessible ECG datasets for ACS prediction.
  • Prompt intervention is crucial for patients with occlusion myocardial infarction (OMI), a severe ACS subtype.

Purpose of the Study:

  • To introduce a comprehensive 12-lead ECG dataset for acute coronary syndrome (ACS) prediction.
  • To provide a baseline deep learning model for occlusion myocardial infarction (OMI) detection.
  • To facilitate AI-driven research and development in cardiovascular diagnostics.

Main Methods:

  • Compiled a dataset of 19,955 ten-second ECG recordings (500 Hz) from 18,909 patients who underwent digital subtraction angiography.
  • Annotated the dataset with labels for ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, unstable angina, OMI, and infarction locations.
  • Developed and open-sourced a baseline deep learning model for OMI detection, validated by physician assessments.

Main Results:

  • Established a large-scale, openly accessible 12-lead ECG dataset specifically for ACS and OMI research.
  • Demonstrated the utility of the dataset by developing and releasing a functional baseline deep learning model for OMI detection.
  • Provided clinical diagnostic benchmarks through expert physician assessments of ACS and OMI identification.

Conclusions:

  • The newly released ECG dataset and baseline AI model represent significant resources for advancing AI applications in acute coronary syndrome diagnosis.
  • This initiative addresses the scarcity of large, labeled ECG datasets, paving the way for more robust AI tools in emergency cardiology.
  • The open-sourced nature of the data and model encourages further research and innovation in AI-powered cardiovascular diagnostics.

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