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Updated: May 6, 2026

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Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
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Management of myopia: a mini-review
Andrzej Grzybowski1,2, Carla Lanca3,4
1Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan, Poland.
Summary
Increased outdoor time is a key strategy for preventing myopia in children. Effective optical and pharmacological treatments can slow myopia progression, with combination therapies showing promise for faster progressors.
Area of Science:
- Ophthalmology
- Pediatric Optometry
- Myopia Control Research
Background:
- Myopia is a growing global health concern, particularly in East Asia.
- Axial elongation drives myopia, increasing risks for serious eye conditions.
- Managing myopia in children is complex due to diverse treatment options.
Purpose of the Study:
- To review current evidence on delaying myopia onset in children.
- To synthesize data on strategies for slowing myopia progression.
- To provide guidance for pediatric myopia management.
Main Methods:
- Conducted a narrative review of English-language studies (2015-2025) and seminal prior trials.
- Included randomized trials, comparative studies, systematic reviews, and guidelines.
- Focused on participants under 18 years, analyzing refractive error and axial length (AL).
Main Results:
- Increased outdoor time consistently reduces myopia incidence and progression.
- Optical interventions (DIMS, dual-focus contacts) are effective vs. single-vision correction.
- Low-dose atropine and orthokeratology show efficacy, with combination therapies potentially enhancing outcomes.
- Red-light therapy shows promise but requires further research on safety and efficacy.
Conclusions:
- A risk-stratified approach combining outdoor time with optical/pharmacological therapy is recommended.
- Future research needs head-to-head trials, longer follow-up, diverse populations, and standardized safety standards.
- Evidence supports integrating lifestyle modifications with advanced treatments for comprehensive myopia management.
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