Heart block after transcatheter septal defect closure in infants under 10 kg: clinical outcomes and management

Related Experiment Video

Updated: May 7, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

3.7K

Sedef Oksuz1, Kaan Yildiz1, Rasit Aktas2

  • 1Department of Pediatric Cardiology, Izmir City Hospital, Izmir, Turkey Department of Pediatric Cardiology Izmir City Hospital Izmir Turkey.

REC, Interventional Cardiology
|May 6, 2026
PubMed

Insights

Heart block is a serious complication after transcatheter closure of perimembranous ventricular septal defects, especially in low-weight pediatric patients. Early detection and management are key for favorable outcomes.

Area of Science:

  • Pediatric Cardiology
  • Interventional Cardiology

Background:

  • Transcatheter device closure is a common treatment for perimembranous ventricular septal defects (VSDs).
  • Heart block is a potential complication following this procedure.

Purpose of the Study:

  • To review the management of heart block after transcatheter device closure of perimembranous VSDs in pediatric patients.
  • To evaluate outcomes of patients who developed complete atrioventricular block or left bundle branch block (LBBB).

Main Methods:

  • Retrospective evaluation of patients who developed heart block post-VSD closure between January 2019 and December 2023.
  • Analysis of treatment strategies and follow-up for complete atrioventricular block and LBBB.

Main Results:

  • All patients who developed heart block weighed less than 10 kg.
  • Complete atrioventricular block was treated with temporary pacing. Postoperative LBBB cases were managed with steroid therapy or surgical device removal.
  • Some LBBB cases required procedural termination or close follow-up.

Conclusions:

  • Heart block after transcatheter VSD closure is a serious complication, particularly in low-weight children.
  • Prompt management, including procedural adjustments, medical therapy, and surgery, can lead to good outcomes.
  • Careful patient selection and diligent follow-up are crucial to mitigate risks.
Abstract

Keywords:
Atrioventricular blockLeft bundle branch blockPediatric patientsPerimembranous ventricular septal defectsTranscatheter closure

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