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Updated: May 7, 2026

Author Spotlight: A Non-Invasive Tool to Assess and Differentiate Fat Patterns in Liver Using 3D Dixon MRI
Published on: October 20, 2023
Subsampled randomized Fourier GaLore for adapting foundation models in depth-driven liver landmark segmentation
Yun-Chen Lin1, Jiayuan Huang2,3, Hanyuan Zhang2
1UCL Hawkes Institute and Dept of Medical Physics and Biomedical Engineering, University College London, London, UK. lyunchen178@gmail.com.
This study introduces a novel depth-guided segmentation framework for laparoscopic liver surgery, improving anatomical structure detection. The method enhances computer-assisted interventions by effectively fusing RGB and depth data for precise surgical guidance.
Area of Science:
- Medical Imaging
- Computer-Assisted Surgery
- Artificial Intelligence in Medicine
Background:
- Accurate anatomical structure detection is crucial for computer-assisted interventions, especially in laparoscopic surgery.
- 2D video limitations in depth perception and landmark localization pose significant challenges.
- Existing methods struggle with fusing RGB and depth features and adapting large vision models to surgical data.
Purpose of the Study:
- To develop a depth-guided segmentation framework for precise anatomical structure delineation in laparoscopic liver surgery.
- To address challenges in fusing RGB and depth data and efficiently adapting foundation models for surgical applications.
- To improve landmark localization and depth perception in 2D surgical video streams.
Main Methods:
- Proposed a dual-encoder framework using SAM2 (RGB) and Depth Anything V2 (depth) for semantic and geometric cues.
- Introduced SRFT-GaLore for efficient fine-tuning of SAM2's high-dimensional attention layers.
- Implemented a cross-attention fusion module to integrate RGB and depth features.
- Validated cross-dataset generalization on L3D and LLSD datasets.
Main Results:
- Achieved 4.85% improvement in Dice Similarity Coefficient (DSC) and 11.78-point reduction in Average Symmetric Surface Distance (ASSD) on the L3D dataset.
- Demonstrated strong cross-dataset robustness and adaptability on the LLSD dataset.
- Outperformed SAM-based baselines, indicating effective generalization to unseen surgical environments.
Conclusions:
- The SRFT-GaLore-enhanced dual-encoder framework enables scalable, precise segmentation in depth-constrained surgical settings.
- Foundation model adaptation shows potential for real-time computer-assisted interventions.
- Future work will explore transformer-based decoders for deeper cross-modal fusion and improved performance.
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