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Updated: May 8, 2026

Cerebellar Regional Dissection for Molecular Analysis
Published on: December 5, 2020
T2 Hyperintensity in the Inferior Olivary and Dentate Nuclei: Novel Imaging Findings in Spinocerebellar Ataxia Type
Riho Fukuda1, Jun Oyama1, Taro Ishiguro2
1Department of Radiology, Institute of Science Tokyo Hospital, Japan.
Abstract:
Spinocerebellar ataxia type 8 (SCA8) is a relatively rare type of autosomal dominant hereditary spinocerebellar degeneration. Previously reported imaging findings have shown isolated cerebellar atrophy. We herein report the case of a patient with a genetically confirmed diagnosis of SCA8 who exhibited T2 hyperintensity in the inferior olivary and dentate nuclei in addition to cerebellar atrophy. To the best of our knowledge, this is the first report of this specific imaging finding associated with SCA8, which may represent a characteristic imaging feature of the disease.
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