Related Experiment Video
Updated: May 8, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Probiotic Effect on Quality of Life, Bowel Habits and Weight Loss after Different Types of Bariatric Surgeries, a
Mostafa Mahmoud Abdelfatah1, Osama Salah Mohammad2, Ismail Ahmed Shafik2
1Kasralainy School of Medicine, Cairo University, Giza, Egypt. mostafa1987@cu.edu.eg.
Introduction:
Obesity is a complex health condition marked by an excessive accumulation of adipose tissue. Bariatric surgery continues to be the most efficacious intervention for attaining significant and enduring weight loss. This study aimed to assess a 6-month probiotics supplementation effect on quality of life (QoL), bowel habits, excess weight loss (EWL) and changes in stool composition and fecal Calprotectin in severely obese patients undergoing different types of bariatric surgeries.
Methods:
This prospective randomized controlled trial involved 200 cases underwent standardized bariatric procedures. Cases were randomized into two equal groups: Probiotic group received either Enterogermina® 6 billion sachets or Lacteol forte® sachets, one sachet twice daily for 6 months postoperatively and control group: Patients received standard postoperative care without probiotics.
Results:
At 1 month postoperatively, the probiotics group showed a significantly higher QOL and EWL% (p < 0.001) compared to controls. At 3 months, the probiotics group had a significantly higher QOL and EWL% (p < 0.001). At 6 months, the probiotics group showed a statistically significant improvements across all measured outcomes, including QOL, BHQ, and EWL% compared to the control group(p < 0.001). Probiotic group had a significantly lower fecal calprotectin compared to control group (p < 0.001).
Conclusion:
The probiotic use post-bariatric surgery offers measurable benefits in QOL, weight loss, and gastrointestinal inflammation, regardless of the surgical type. Although procedures like RYGB and OAGB yield superior weight loss, they may induce higher gut inflammation. Meanwhile, sleeve gastrectomy appears to be the most gut-friendly in terms of inflammatory markers and bowel consistency.
More Related Videos
Related Concept Videos
Probiotics
Drugs for Treatment of Constipation-Predominant IBS
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome III: Medical and Nursing Management
