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Comparative evaluation of cetylpyridinium chloride-modified EDTA, sequential, and continuous chelation on smear layer
Huda Hassan Khairy1, Alaa Jawad Kadhim1
1Department of Restorative and Aesthetic Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Objectives:
Evaluate the effectiveness of cetylpyridinium chloride (cpc) addition to EDTA (CPC-modified EDTA) compared to standard sequential (SC) and continuous (CC) chelation protocols in removing the smear layer and dentine erosion.
Materials And Methods:
The concentration of CPC was determined by pilot research based on surface tension and contact angle (0.2%). In the current study, sixty single roots-human mandibular premolars were divided into five groups (n = 12) according to irrigation protocol:sequential chelation using CPC-modified EDTA; conventional Sequential chelation using EDTA; continuous chelation using NaOCl mixed with HEDP; NaOCl alone and normal saline alone. The roots were separated longitudinally to evaluate the smear layer and dentine erosion utilizing SEM; and the obtained data were analyzed using Kruskal-Wallis and Mann-Whitney U tests.
Results:
Similar effectiveness was observed between the sequential and continuous chelation protocols when EDTA alone was used (P > 0.05), However, CPC-modified EDTA used in the sequential protocol showed significantly greater smear layer removal than continuous chelation protocol particularly in the apical third(P < 0.05), while a similar effect on dentin erosion was observed among groups (P > 0.05).
Conclusions:
The addition of a surfactant to the root canal irrigant showed better results; however, the difference was statistically significant only in the apical third At the apical third, CPC-modified EDTA demonstrated significantly better smear layer removal compared to the CC protocol, while showing a similar effect on dentin erosion compared to both SC and CC protocols.
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