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Updated: May 9, 2026
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Contrast Induced Nephropathy in Trauma: A Real Phenomenon?
Richard H Lewis1, Braden McIntosh2, Shahrzad Talebinejad1
1Department of Trauma Surgery, Our Lady of the Lake Regional Medical Center, Baton Rouge, LA, USA.
The American Surgeon
|May 8, 2026
Summary
In trauma patients, receiving intravenous contrast during initial evaluation did not increase the risk of acute kidney injury (AKI). This finding is crucial for understanding contrast media safety in critically ill patients.
Area of Science:
- Nephrology
- Trauma Surgery
- Radiology
Background:
- Acute kidney injury (AKI) is a significant concern in trauma patients.
- The role of iodinated contrast media in AKI development within this population requires clarification.
Purpose of the Study:
- To investigate the association between contrast administration and AKI in trauma patients.
- To identify predictors of AKI in this cohort.
Main Methods:
- Retrospective analysis of trauma patients at a level one trauma center.
- Stratification based on contrast administration during initial diagnostic workup.
- Multivariable logistic regression to assess AKI predictors.
Main Results:
- 551 patients received contrast, 288 did not; 6.9% developed AKI.
- Contrast-exposed patients had higher injury severity and baseline creatinine.
- Contrast administration was associated with lower AKI rates (5.6% vs 9.4%).
Conclusions:
- Intravenous contrast administration was not associated with increased AKI risk in trauma patients.
- Age, blood transfusions, systolic blood pressure, and creatinine predicted AKI.
- Contrast use appears safe regarding AKI in this setting.
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