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Related Concept Videos

Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...

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Related Experiment Video

Updated: May 9, 2026

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
09:42

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury

Published on: March 27, 2026

Mapping Population-Level Differences in Brachial Plexus Birth Injury: An International Meta-Analysis.

Holly Cordray1, Miguel Fiandeiro1, Seungjun Lee2

  • 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

The Journal of Hand Surgery
|May 8, 2026
PubMed
Summary
This summary is machine-generated.

Brachial plexus birth injuries (BPBI) affect 1.4 per thousand births globally, with significant regional variations. Further research into population-level factors is needed to understand and potentially reduce BPBI incidence.

Keywords:
Brachial plexus birth injuryepidemiologyglobal healthneonatologyorthopedics

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Area of Science:

  • Pediatrics
  • Neurology
  • Public Health

Background:

  • Brachial plexus birth injuries (BPBI) often occur without identifiable prenatal risk factors.
  • Understanding the global incidence of BPBI is crucial for identifying population-level predictors.

Purpose of the Study:

  • To map the worldwide incidence of brachial plexus birth injuries (BPBI).
  • To identify population-level predictors for BPBI.

Main Methods:

  • Systematic review and meta-analysis of cross-sectional studies on BPBI incidence.
  • Searched PubMed, Embase, Cochrane, and Web of Science databases.
  • Meta-regression used to compare population-based differences in incidence.

Main Results:

  • Pooled data from 71.5 million births across 30 countries.
  • Composite international BPBI incidence was 1.4 per thousand births (95% CI, 1.3-1.6).
  • Significant international variation observed, with country of birth explaining 34.2% of variance; 18.4% of cases persisted beyond one year.

Conclusions:

  • Significant regional variations in BPBI incidence warrant further investigation into population-level influences.
  • Exploration of health systems, environmental, sociodemographic, and genetic factors is recommended.
  • New research questions are needed to address the unpredictability of BPBI incidence.