Related Experiment Video
Updated: May 9, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Coverage Limitations for Use of Urine Drug Testing in a State Medicaid Program.
Michael A Incze1, Sarah R Tingley2, John Neuhaus3
1Division of General Internal Medicine, Department of Medicine, University of Utah School of Medicine, Salt Lake City.
A policy limiting Medicaid reimbursement for urine drug testing (UDT) significantly reduced testing frequency and costs. This initiative decreased low-value care without impacting substance use disorder treatment outcomes.
Area of Science:
- Health Services Research
- Health Economics
- Substance Use Disorder Treatment
Background:
- Urine drug testing (UDT) is widely used in substance use disorder (SUD) treatment.
- Evidence guiding optimal UDT use is limited, raising concerns about low-value care.
- The impact of reimbursement policies on UDT utilization and outcomes is not well understood.
Purpose of the Study:
- To evaluate the association between a statewide policy limiting Medicaid reimbursement for UDT and subsequent changes in testing frequency, expenditures, and clinical outcomes.
- To assess the impact of the policy on utilization of presumptive and definitive UDT.
- To compare trends in UDT utilization with a control procedure (colonoscopy) and examine concomitant trends in overdose encounters and medication for opioid use disorder (MOUD) prescriptions.
Main Methods:
- A serial cross-sectional study design was employed using Louisiana Medicaid beneficiary data from July 2017 to February 2020.
- Analysis involved comparing observed trends post-policy enactment (July 2019) with pre-enactment trends, using best-fit lines and controlling for time and intervention period interactions.
- Colonoscopy rates served as a matched control procedure; overdose encounters and MOUD prescriptions were also assessed.
Main Results:
- Following the policy change, monthly rates of total UDT utilization significantly decreased (difference, -1.70 tests per month per 1000 beneficiaries; P < .05).
- Significant reductions were also observed for presumptive UDT (difference, -1.05; P < .05) and definitive UDT (difference, -0.65; P < .05) compared to colonoscopy trends.
- UDT expenditures decreased significantly, resulting in an estimated $14.8 million in savings over the 7-month post-enactment period; no significant changes in MOUD receipt or overdose encounters were noted.
Conclusions:
- A state policy limiting Medicaid reimbursement for UDT was associated with substantial reductions in testing utilization and associated healthcare expenditures.
- The policy effectively reduced potentially low-value care without adversely affecting key clinical outcomes like MOUD receipt or overdose encounters.
- Findings suggest that carefully designed reimbursement policies can optimize the value of UDT in SUD treatment, warranting further investigation into best practices.
Related Concept Videos
Urine Studies I: Urinalysis
Drug Elimination by Renal Route: Tubular Reabsorption
Pharmacokinetics in Pediatric Patients: Drug Excretion
Urine Studies II: Urine Culture and Sensitivity Test
Therapeutic Drug Monitoring: Drug Analysis Methods
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...

