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The ecology and evolution of sub-exponential replicators.

Bianka Kovács1,2, György Barabás1,3, Géza Meszéna1,4

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Summary

Oligonucleotide replicators model early life. A new model reveals limits on diversity, showing high concentrations favor exponential growth, potentially leading to competitor extinction in prebiotic environments.

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Area of Science:

  • * Origin of Life Studies
  • * Chemical Evolution
  • * Systems Chemistry

Background:

  • * Oligonucleotide chemical replicator molecules are key models for prebiotic evolution.
  • * Existing models present conflicting assumptions and predictions regarding their eco-evolutionary dynamics.
  • * A comprehensive understanding of these systems is needed to clarify their role in early life formation.

Purpose of the Study:

  • * To develop a model of oligonucleotide replicator systems accounting for reversible template-copy association.
  • * To investigate the impact of system and resource concentrations on replicator diversity and growth dynamics.
  • * To explore the competitive interactions between sub-exponential and exponential replicators.

Main Methods:

  • * Development of a mathematical model incorporating reversible association and self-inhibition.
  • * Analysis of system dynamics under varying concentrations of replicators and resources.
  • * Simulation of competitive scenarios between different replicator growth rates.

Main Results:

  • * Reversible association leads to self-inhibition and sub-exponential growth, imposing limits on attainable diversity.
  • * Increased system concentration enhances diversity, while increased resource concentration decreases it.
  • * Exponentially growing replicators outcompete sub-exponential ones in high-concentration environments, irrespective of copying rate.

Conclusions:

  • * The model clarifies eco-evolutionary limits in replicator systems, challenging simplified predictions.
  • * Concentration dynamics play a critical role in determining species diversity and competitive success.
  • * Exponential replicators can dominate prebiotic environments, potentially leading to competitive exclusion of slower-growing species.