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Pediatric Femoral Neck Fractures: Unrecognized Association With Autism Spectrum and Neurodevelopmental Disorders.
Abdulsamet Emet1,2, Grace Armet1, Connor Luck1
1Departments of Orthopaedic Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA.
Pediatric femoral neck fractures are linked to autism spectrum disorder (ASD) and neurodevelopmental disorders (NDD). Children with ASD/NDD have higher comorbidity rates and unique injury risks, impacting fracture outcomes.
Area of Science:
- Orthopedic Surgery
- Pediatric Orthopedics
- Neurodevelopmental Pediatrics
Background:
- Pediatric femoral neck fractures are uncommon injuries.
- Autism spectrum disorder (ASD) and neurodevelopmental disorders (NDD) are increasingly recognized in pediatric populations.
- Understanding the interplay between these conditions is crucial for comprehensive care.
Purpose of the Study:
- To identify pediatric femoral neck fractures.
- To determine the prevalence of ASD and NDD in these patients.
- To assess the impact of ASD/NDD on clinical and radiographic outcomes.
Main Methods:
- Retrospective review of 140 pediatric patients with femoral neck fractures.
- Data collection included demographics, clinical and radiographic findings, and ASD/NDD status.
- Statistical analysis using t tests and χ2 tests (P<0.05).
Main Results:
- 28% of patients with femoral neck fractures had ASD or NDD.
- ASD/NDD patients showed increased neurological/gastrointestinal comorbidities and low vitamin D.
- Home-related injuries were more prevalent in the ASD/NDD group.
- Complications like infection and avascular necrosis were infrequent and similar between groups.
Conclusions:
- A significant association exists between pediatric femoral neck fractures and ASD/NDD.
- Children with ASD/NDD present with distinct medical comorbidities and injury patterns.
- These findings highlight unique risk profiles and inform management strategies for this patient group.
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