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Related Concept Videos

Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Uterine Tubes01:16

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Ovarian Cycle01:27

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...

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Global Review on the Use of AI in IVF Laboratories.

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Fibroids and pregnancy.

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Letter to the editor: Anovulatory bleeding and the spectrum of bleeding disorders: Understanding heavy menstrual bleeding in adolescents.

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Related Experiment Video

Updated: May 10, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Fibroids and infertility.

Edgar Mocanu1,2, Basil Tarlatzis3, Dov Feldberg4

  • 1Rotunda Hospital, Dublin, Ireland.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics
|May 9, 2026
PubMed
Summary
This summary is machine-generated.

Uterine fibroids affect fertility differently based on type and location. Surgical management is recommended for certain fibroid types in women seeking pregnancy, while uterine artery embolization is not advised.

Keywords:
IVFfemale infertilityfibroidsmyomectomypregnancysubmucosaluterine dysbiosis

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Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
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Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

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Last Updated: May 10, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

Area of Science:

  • Reproductive Medicine
  • Gynecology
  • Obstetrics

Background:

  • Uterine fibroids are common benign tumors that can significantly impact female fertility.
  • The location and type of fibroids influence their effect on conception and pregnancy outcomes.
  • Understanding these impacts is crucial for guiding treatment decisions in women with fertility concerns.

Purpose of the Study:

  • To elucidate the mechanisms by which uterine fibroids affect fertility.
  • To compare the impact of different fibroid types (subserosal, intramural, submucosal) on pregnancy.
  • To review current treatment recommendations for uterine fibroids in women desiring pregnancy.

Main Methods:

  • Review of existing literature on uterine fibroids and fertility.
  • Analysis of the impact of fibroid location and type on pregnancy rates and complications.
  • Evaluation of the safety and efficacy of various treatment modalities.

Main Results:

  • Submucosal fibroids severely reduce pregnancy chances and increase complications.
  • Intramural fibroids negatively affect pregnancy likelihood and outcomes.
  • Surgical management of FIGO Types 0-3 fibroids is the preferred approach for fertility preservation.
  • Uterine artery embolization is not recommended for women seeking pregnancy.

Conclusions:

  • Fibroid type and location are critical determinants of fertility impact.
  • Myomectomy is the gold standard for specific fibroid types in women desiring pregnancy.
  • Assisted reproductive technologies may be challenging with large fibroids obscuring ovaries.
  • Cesarean delivery is recommended if the uterine cavity was opened during myomectomy.