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Updated: May 12, 2026

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
07:40

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis

Published on: March 20, 2021

Statistical design and data analysis for the effect of multiple doses of a treatment on renal functions using a

Meiyu Shen1, Xiaoyu Cai1

  • 1Division of Biometrics VI, Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.

Journal of Biopharmaceutical Statistics
|May 11, 2026
PubMed

Keywords:
Statistical noninferiority analysismultiple dosespharmacodynamic biomarkerssafety evaluation

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