Related Experiment Video
Updated: May 12, 2026
A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
Published on: January 12, 2019
Xenografts and platelet-rich fibrin impact on maxillary sinus augmentation: A comparative clinical histomorphometric
Abhishek Motimath1, Sonal S2, Mouneshkumar C D3
1Department of Oral and Maxillofacial Surgery, KLE V K Institute of Dental Sciences, Karnataka, India.
Abstract:
Insufficient posterior maxillary bone height limits implant placement in atrophic ridges. Therefore, it is of interest to compare deproteinized bovine bone mineral (DBBM) versus DBBM with advanced platelet-rich fibrin (A-PRF) in 60 sinuses across 30 patients undergoing lateral window sinus augmentation. Histomorphometry showed greater new bone formation [42.8 (6.4%) vs. 31.2 (5.9%), p=0.001] and less residual graft [28.4 (4.7) vs. 41.6 (6.1%), p=0.001] in the A-PRF group. Test sites also demonstrated improved bone density, graft height stability and 100% implant survival at 9 months. A-PRF accelerates bone regeneration and reduces graft resorption in sinus augmentation, advancing biologic augmentation strategies.