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Published on: June 10, 2025
The relationship between discharge destination and rehospitalization in Chinese patients with heart failure: a cohort
Xia Yun1, Shaojie Bi2, Xiaohua Shi1
1Department of Geriatrics, The Second Qilu Hospital of Shandong University, Jinan, China.
Insights
Discharging heart failure patients to healthcare facilities, rather than home, increases their risk of readmission. This finding highlights discharge destination as a key factor for predicting heart failure readmissions.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- High heart failure (HF) readmission rates pose a significant public health challenge.
- Limited research exists on the impact of discharge destination on HF readmissions in Chinese populations.
Purpose of the Study:
- To investigate the association between discharge destination and readmission rates in heart failure patients in China.
- To identify if discharge to a healthcare facility increases the risk of heart failure readmission compared to discharge home.
Main Methods:
- Retrospective cohort study of 836 heart failure patients from December 2016 to June 2019.
- Patients were categorized by discharge destination: home versus healthcare facility.
- Cox proportional hazards regression and Kaplan-Meier analyses were employed to assess readmission risk at 28 days, 3 months, and 6 months.
Main Results:
- Discharge to a healthcare facility was independently associated with a significantly higher risk of readmission within 6 months (adjusted HR 1.26, P=0.009).
- This association persisted for readmissions at 3 months (HR 1.26, P=0.034) and 28 days (HR 1.53, P=0.032).
- Kaplan-Meier analysis and subgroup analyses confirmed the robustness of these findings.
Conclusions:
- Discharge destination is a critical factor influencing heart failure patient outcomes.
- Patients discharged to healthcare facilities face an elevated risk of heart failure readmission.
- Clinical practice should consider discharge destination as an important indicator for readmission risk stratification.
Background:
The high readmission rate among heart failure (HF) patients is a significant concern, but limited research has explored the relationship between discharge destination and readmission rates in Chinese HF patients.
Objective:
To examine the association between discharge destination and readmission in HF patients.
Methods:
This retrospective cohort study analyzed data from 2,008 HF patients admitted to the Fourth People's Hospital of Zigong City, China, between December 2016 and June 2019. Patients were divided into two groups based on their discharge destination: home and healthcare facility. The primary outcome was readmission within 6 months, with secondary outcomes at 3 months and 28 days. Cox proportional hazards regression and Kaplan-Meier curves were used to assess the relationship, with additional subgroup and interaction analyses for robustness.
Results:
A total of 836 patients with HF were enrolled in this study. Among them, 638 patients were discharged to home, while 198 patients were discharged to healthcare facilities. The multivariable Cox proportional hazards regression model revealed that discharge to healthcare facilities were independently associated with a higher readmission risk compared with discharge to home, adjusted HR 1.26, 95% CI 1.06-1.50, P = 0.009 for readmission within 6 months. Similar trends were observed for readmission within 3 months (HR: 1.26, 95% CI: 1.02-1.55, P = 0.034) and 28 days (HR: 1.53, 95% CI: 1.04-2.26, P = 0.032). Kaplan-Meier analysis (log-rank test P = 0.011) supported the above findings, and the association remained robust in subgroup and sensitivity analyses.
Conclusion:
This study demonstrated that discharge to a healthcare facility was independently associated with an increased readmission risk among HF patients. Discharge destination should be considered as a potential indicator of readmission risk in clinical practice.
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