Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 12, 2026

Transcranial Direct Current Stimulation for Online Gamers
06:01

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

Altered Resting-State Functional Connectivity in Internet Gaming Disorder: Convergent Evidence and Independent

Jiawen Tian1,2, Hui Zhang1,2, Xinyu Wang1,2

  • 1Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Addictive Behaviors Reports
|May 11, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Interplay Between Sleep Disturbance, Glymphatic Dysfunction and Altered Brain Networks in Internet Gaming Disorder: A Multimodal Neuroimaging Study.

Addiction biology·2026
Same author

Altered effective connectivity in internet gaming disorder and its predictive value for clinical severity: A spectral DCM study.

Brain research bulletin·2026
Same author

MRI features of craniopharyngiomas in different age groups and pathological subtypes.

Frontiers in oncology·2026
Same author

Disordered connectivity configuration of triple-network model and visual-network in tobacco use disorder.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same author

Cortical Structure Alterations in Young People With Mild Internet Gaming Disorder.

Addiction biology·2026
Same author

MRI assessment of intrinsic neural timescales in male alcohol use disorder patients.

Frontiers in psychiatry·2026

Resting-state functional connectivity (RSFC) in Internet Gaming Disorder (IGD) shows consistent alterations in frontal and midline brain regions. These findings in individuals with IGD highlight potential neural markers for the condition.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Medical Imaging

Background:

  • Internet Gaming Disorder (IGD) is a growing global concern.
  • Previous resting-state functional connectivity (RSFC) studies on IGD have yielded inconsistent results.
  • Robust neural alterations in IGD require synthesis and independent validation.

Purpose of the Study:

  • To synthesize existing RSFC findings in IGD using meta-analysis.
  • To validate convergent findings in an independent cohort of individuals with IGD.
  • To identify reproducible neural alterations associated with IGD.

Main Methods:

  • A coordinate-based meta-analysis using anisotropic effect size-signed differential mapping (AES-SDM) was conducted on 17 studies.
  • Regions of interest (middle frontal gyrus, medial frontal/cingulate regions) were identified for independent validation.

More Related Videos

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking
13:40

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Published on: December 16, 2010

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Related Experiment Videos

Last Updated: May 12, 2026

Transcranial Direct Current Stimulation for Online Gamers
06:01

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking
13:40

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Published on: December 16, 2010

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

  • Resting-state fMRI data from 58 individuals with IGD and 38 controls were analyzed using seed-based connectivity and correlation analyses.

    • Main Results:

    • Meta-analysis revealed convergent RSFC abnormalities in the median cingulate/paracingulate region and bilateral middle frontal gyrus.
    • Independent validation confirmed significant RSFC alterations in individuals with IGD within these regions.
    • Connectivity strength in the middle frontal gyrus was positively correlated with Internet Addiction Test scores.

    Conclusions:

    • Convergent evidence supports abnormal resting-state connectivity in IGD, particularly in frontal and midline regions.
    • These regions are crucial for executive control and self-referential processing.
    • Independent validation underscores the reproducibility and clinical relevance of these specific neural alterations in IGD.