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Stem cell therapy alleviates hair loss caused by COVID-19 vaccination

Suyeon Kim1

  • 1Gangnam Seran Clinic, Seoul, Korea.

Journal of Exercise Rehabilitation
|May 11, 2026
PubMed

Insights

This study reports a successful treatment for hair loss following coronavirus disease 2019 (COVID-19) vaccination using stem cell therapy. Autologous CD34+ HPCF and umbilical cord blood-derived mesenchymal stem cells (UC-MSCs) significantly improved hair regrowth.

Area of Science:

  • Regenerative Medicine
  • Dermatology
  • Immunology

Background:

  • Hair loss is a potential side effect of coronavirus disease 2019 (COVID-19) vaccination.
  • Novel therapeutic strategies are needed to address vaccine-induced alopecia.

Purpose of the Study:

  • To evaluate the efficacy of autologous CD34+ enriched hematopoietic progenitor cell fraction (CD34+ HPCF) and umbilical cord blood-derived mesenchymal stem cells (UC-MSCs) in treating COVID-19 vaccine-induced hair loss.
  • To assess the safety and tolerability of this combined stem cell therapy.

Main Methods:

  • A single female patient with generalized hair loss post-COVID-19 vaccination received a combined treatment regimen.
  • Subcutaneous injections of autologous CD34+ HPCF were administered weekly for 10 sessions.
  • Intravenous and subcutaneous administration of UC-MSCs occurred at weeks 5 and 10.

Main Results:

  • The patient experienced significant improvement in hair loss after 12 weeks of treatment.
  • No significant adverse effects were reported during the treatment period.
  • The combined therapy demonstrated a positive impact on vaccine-induced alopecia.

Conclusions:

  • Autologous CD34+ HPCF and UC-MSC injections represent a promising therapeutic approach for hair loss triggered by COVID-19 vaccination.
  • This case study highlights the potential of regenerative medicine in managing vaccine-related adverse events.

Keywords:
CD34+ HPCFCOVID-19 vaccinationHair loss treatmentStem cell therapyUC-MSCs

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