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Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
Published on: May 4, 2020
Observed frequency of increased iron indices and associated factors in welders
Yusuf Samir Hasanli1, Selin Çakmakci Karakaya2
1Occupational Diseases Unit, Department of Internal Diseases, Ankara Etlik City Hospital, Ankara, Türkiye.
Abstract:
Increased iron indices among welders are underrecognized. This study investigated their frequency and associated factors in an observational cross-sectional study including 55 male welders. Increased iron indices were defined as serum ferritin >400 µg/L and/or TS ≥45%. Standard statistical and regression analyses were used. Increased iron indices were identified in 25.5% of welders. Compared to those with normal indices, affected welders had longer employment duration. Iron parameters were significantly higher in the increased group (serum iron 139.6 vs. 93.3 µg/dL, ferritin 498.9 vs. 142.3 µg/L, TS 47.7% vs. 28.9%; all p<0.001). Liver enzymes were also higher in this group. Pulmonary siderosis was more prevalent (64.3% vs. 31.7%; p=0.032) and associated with increased iron indices (OR 3.88 [1.08-13.89]; p=0.037). Use of respiratory protective equipment was associated with lower frequency. Increased iron indices are common in welders, particularly with longer exposure and pulmonary siderosis, suggesting a need for routine monitoring.
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