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A High-throughput Assay for the Prediction of Chemical Toxicity by Automated Phenotypic Profiling of Caenorhabditis elegans
Published on: March 14, 2019
Moving towards Next-Generation Environmental Risk Assessment of Chemicals in China
Baile Xu1, Bing Zhang2, Xiaojing Li3
1Unilever, Safety, Environmental and Regulatory Science (SERS), Sharnbrook, MK44 1LQUnited Kingdom.
Integrated Environmental Assessment and Management
|May 11, 2026
Summary
China faces environmental challenges from industrial growth. Next-Generation Environmental Risk Assessment (environmental NGRA) offers a promising, exposure-led approach to manage chemical risks and protect health. This perspective outlines implementation strategies.
Area of Science:
- Environmental Science
- Risk Assessment
- Toxicology
Background:
- Rapid industrialization in China has increased chemical use, posing significant environmental and health risks.
- Current risk assessment and management strategies struggle to keep pace with these evolving challenges.
Purpose of the Study:
- To review the progress and challenges of implementing Next-Generation Environmental Risk Assessment (environmental NGRA) in China.
- To identify key opportunities and prioritized actions for advancing environmental NGRA in the Chinese context.
Main Methods:
- The study is a perspective piece based on the first multi-stakeholder workshop on environmental NGRA in China.
- It involved reviewing scientific advancements and regulatory applications, focusing on spatially explicit exposure modeling and New Approach Methodologies (NAMs).
Main Results:
- Implementation of environmental NGRA in China faces scientific and regulatory hurdles.
- Key recommendations include establishing a multi-stakeholder forum, developing a national framework and roadmap, creating integrated case studies, and fostering international collaboration.
Conclusions:
- Environmental NGRA presents a crucial framework for enhancing human and environmental safety in China.
- Advancing environmental NGRA requires a coordinated, multi-faceted approach involving scientific, regulatory, and international cooperation.
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