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Acute-Care Utilization and Cost Offsets Associated With Language-Concordant, Pharmacist-Integrated Care Management
Sasha R Sioni1,2,3, Lesley Manson1, Nicholas Arledge4
1College of Health Solutions, Arizona State University, Phoenix, Arizona, USA.
Health Services Research
|May 11, 2026
Summary
A pharmacist-integrated care program reduced hospital admissions and emergency department visits in safety-net clinics. This intervention demonstrated significant cost savings, offering a strong return on investment for high-need patients.
Area of Science:
- Health Services Research
- Pharmacoeconomics
- Health Equity
Background:
- Safety-net clinics serve vulnerable populations with complex health needs.
- Effective care management programs are crucial for improving outcomes and controlling costs in these settings.
- Language concordance and integrated care models show promise for enhancing patient engagement and effectiveness.
Purpose of the Study:
- To evaluate the utilization and economic impact of a language-concordant, pharmacist-integrated care-management program.
- To assess the program's effectiveness and equity across different language groups and insurance statuses.
Main Methods:
- Retrospective cohort study emulating a target trial in Phoenix safety-net clinics (March 2022-September 2023).
- Utilized inverse probability weighting and doubly robust Poisson difference-in-differences analysis.
- Linked electronic health records, claims data, HIE alerts, and pharmacist logs for 526 high-need, high-cost adults.
Main Results:
- Reduced hospital admissions (IRR, 0.50) and emergency department visits (IRR, 0.47) within 60 days.
- Estimated net savings of $6421 per enrollee with a 13.66:1 return on investment.
- Similar positive trends observed in the Spanish-preferring subgroup, with no statistically significant interaction effects.
Conclusions:
- The language-concordant, pharmacist-integrated program effectively reduced short-term hospital use in safety-net settings.
- The program demonstrated substantial near-term cost offsets, indicating economic viability.
- Findings support the integration of pharmacist-led, language-concordant care management for high-need populations.
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