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Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
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Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
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Update on spasticity: part 1 - background and diagnosis.

Ikechukwu Chukwuocha1, Krishnan Padmakumari Sivaraman Nair2

  • 1Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Drug and Therapeutics Bulletin
|May 11, 2026
PubMed
Summary
This summary is machine-generated.

Spasticity, a condition of increased muscle tone due to central nervous system injury, can cause pain and immobility. Early recognition is key to managing its effects on quality of life.

Keywords:
Cerebrovascular DisordersMovement disordersNeoplasmsNeuromuscular DiseasesTherapeutics

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Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
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Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
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Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

Published on: April 18, 2011

Area of Science:

  • Neurology
  • Rehabilitation Medicine

Background:

  • Spasticity is a common, complex condition resulting from central nervous system (CNS) injury.
  • It presents as a velocity-dependent increase in muscle tone and can be an early symptom of various neurological disorders.

Purpose of the Study:

  • To provide a comprehensive overview of spasticity.
  • To cover its causes, pathophysiology, clinical features, diagnosis, impact, and measurement.

Main Methods:

  • This is a review article.
  • It synthesizes existing knowledge on spasticity from relevant literature.

Main Results:

  • Spasticity's clinical spectrum varies widely, from mild to severe hypertonia.
  • Severe spasticity can lead to significant complications including pain, contractures, and joint immobility.
  • Accurate differentiation from other conditions like rigidity is crucial.

Conclusions:

  • Early identification and understanding of spasticity are vital for mitigating its negative impact on functional independence and patient quality of life.
  • This review offers a foundational understanding for clinicians and researchers.