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Related Experiment Video

Updated: May 13, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

Using Large Language Models to Determine Reasons for Missed Colon Cancer Screening Follow-Up.

Christopher Y K Williams, Urmimala Sarkar, Julia Adler-Milstein

    Joint Commission Journal on Quality and Patient Safety
    |May 11, 2026
    PubMed
    Summary
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    Large language models (LLMs) can automate identifying why patients miss follow-up colonoscopies after abnormal stool tests. This technology shows promise for improving cancer screening quality by reducing manual chart review burdens.

    Area of Science:

    • Medical Informatics
    • Artificial Intelligence in Healthcare
    • Cancer Screening Quality Improvement

    Background:

    • Identifying reasons for missed preventive care, like follow-up colonoscopy after abnormal stool-based screening, is crucial for quality improvement.
    • Manual chart review for these care gaps is time-consuming and costly.
    • This study explores using large language models (LLMs) to automate this process.

    Purpose of the Study:

    • To demonstrate the potential of LLMs in automating the identification of documented reasons for colonoscopy follow-up gaps.
    • To assess if LLMs can accurately classify these reasons into clinically meaningful categories.

    Main Methods:

    • A cross-sectional study involving patients aged 45+ with abnormal fecal immunochemical/occult blood tests (FIT/FOBT) who did not receive a colonoscopy within 90 days.

    Related Experiment Videos

    Last Updated: May 13, 2026

    Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
    07:13

    Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

    Published on: April 18, 2025

  • Investigated LLM's ability to determine if reasons for lack of follow-up colonoscopy were documented in clinical notes.
  • Assessed LLM's accuracy in classifying documented reasons.
  • Main Results:

    • Out of 846 patients, 23.3% had explicit reasons documented for not having a colonoscopy.
    • LLM classification accuracy reached 89.0%.
    • Common reasons included patient refusal (35.2%), comorbidities (18.7%), and unavailability (16.8%).

    Conclusions:

    • LLMs can accurately categorize reasons for missed follow-up colonoscopies after abnormal FIT/FOBT.
    • LLMs show potential for automating chart review in quality improvement initiatives for colorectal cancer screening.