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Related Concept Videos

The Pineal Gland01:02

The Pineal Gland

The pineal gland, a diminutive endocrine structure named for its pinecone-shaped appearance, is situated atop the third ventricle within the diencephalon region of the forebrain. This gland, composed of secretory cells known as pinealocytes arranged in compact cords and clusters around dense particles of calcium salts, plays a pivotal role in hormonal regulation.
The primary secretion of the pineal gland is the hormone melatonin, derived from serotonin. The concentration of melatonin in the...

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Percutaneous Vertebral Expansion with the SpineJack Device in Adolescents: A Feasibility Case Series.

Journal of vascular and interventional radiology : JVIR·2026
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Dorsal midline ectopic mammary tissue as a cutaneous marker of spinal dysraphism: intradural lipoma and tethered cord in a child with literature review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
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History of Treatment of Pineal Tumors.

Advances and technical standards in neurosurgery·2026
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Incidence of Pineal Tumors.

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Anatomy and Microsurgical Anatomy of the Pineal Region.

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The Pinealoprive Syndrome: Myth or Reality?

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Updated: May 13, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point
03:13

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Published on: June 28, 2024

Decisional Tree for Pineal Tumors.

Carmine Mottolese1, Federico Di Rocco2, Alexandru Szathmari2

  • 1Pediatric Neurosurgical Service, "Woman, Child, Mother" Hospital, Rockefeller Medical School, Lyon, France. carmine.mottolese@chu-lyon.fr.

Advances and Technical Standards in Neurosurgery
|May 11, 2026
PubMed
Summary
This summary is machine-generated.

Accurate diagnosis of pineal tumors involves imaging like MRI and testing tumor markers. Multidisciplinary teams ensure optimal treatment, balancing surgery, chemotherapy, and radiotherapy based on tumor type and patient age.

Keywords:
ChemotherapyDecisional treePineal tumorsRadiotherapy

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Area of Science:

  • Neuro-oncology
  • Radiology
  • Pediatric Oncology

Background:

  • Pineal tumors are rare central nervous system neoplasms.
  • Effective management requires accurate diagnosis and tailored treatment strategies.

Purpose of the Study:

  • To outline diagnostic and therapeutic approaches for pineal tumors.
  • To emphasize the importance of multidisciplinary care for these rare tumors.

Main Methods:

  • Routine radiological studies including cerebral MRI and spinal imaging.
  • Biochemical analysis of pineal markers (alpha-fetoprotein, hCG) in blood and cerebrospinal fluid (CSF).
  • Consideration of patient age and tumor characteristics.

Main Results:

  • Cerebral MRI is the gold standard for diagnosis.
  • Elevated pineal markers indicate germ cell tumors, potentially avoiding surgery.
  • Age influences tumor prevalence, with specific lesions more common in pediatric or adult populations.

Conclusions:

  • Multidisciplinary team discussions are crucial for treatment decisions, even in emergencies.
  • Treatment is stratified: surgery for benign lesions, chemotherapy/radiotherapy for malignant tumors based on histology and genetics.