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Related Concept Videos

Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Cellular Injury II: Classification01:21

Cellular Injury II: Classification

Cellular injury is any process that disrupts a cell’s ability to maintain homeostasis, leading to structural or functional changes. It is broadly classified based on etiology (cause) and mechanism of damage.Classification by EtiologyCellular injury may result from several causes. Hypoxic injury happens due to reduced oxygen delivery, most commonly from inadequate blood supply, such as arterial obstruction; for example, coronary artery thrombosis can cause myocardial infarction. Chemical injury...

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A Novel In Vitro Model of Blast Traumatic Brain Injury
08:59

A Novel In Vitro Model of Blast Traumatic Brain Injury

Published on: December 21, 2018

Blast Injuries.

Neta Cohen1,2, Eyal Hashavia3,4, Uri Neeman5

  • 1Pediatric Emergency Medicine Department, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. netaco@tlvmc.gov.il.

Advances and Technical Standards in Neurosurgery
|July 2, 2026
PubMed
Summary
This summary is machine-generated.

Blast injuries cause multisystem damage from explosions, requiring a multidisciplinary approach for effective trauma care. Understanding blast physics and injury patterns improves outcomes for military and civilian victims.

Keywords:
Blast injuriesBlast lung injuryEmergency medicineMultisystem injuryTraumatic brain injury (TBI)

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Area of Science:

  • Trauma Care
  • Explosion Medicine
  • Emergency Medicine

Background:

  • Blast injuries are complex, causing multisystem damage due to penetrating, blunt, thermal, and barotrauma.
  • Increasing global incidents of explosions raise concerns for military and civilian populations.
  • Effective management requires a multidisciplinary approach integrating clinical experience and evidence.

Purpose of the Study:

  • To provide a comprehensive framework for evaluating and managing blast injuries.
  • To detail injury mechanisms, classification, and organ-specific impacts.
  • To present a pragmatic protocol for initial trauma bay management.

Main Methods:

  • Integration of clinical experience, current evidence, and established guidelines.
  • Focus on epidemiology, injury mechanisms, and organ-specific effects (neurotrauma, pulmonary, cardiovascular, auditory, ocular, musculoskeletal).
  • Development of a trauma bay management protocol emphasizing early recognition and intervention.

Main Results:

  • Blast injuries present unique challenges due to combined injury types.
  • Organ-specific impacts require targeted management strategies.
  • A coordinated, multidisciplinary approach is crucial for optimal patient outcomes.

Conclusions:

  • A deeper understanding of blast physics and injury patterns is essential.
  • Advocacy for a research consortium to refine management strategies and optimize patient outcomes.
  • Improved survival and long-term recovery for blast victims through enhanced clinical understanding and treatment.