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Updated: May 13, 2026
Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 3. Aerobiology
Published on: October 3, 2016
The evolution of the control of airborne infection in operating rooms
William Whyte1, Cesira Pasquarella2
1University of Glasgow, Glasgow, UK.
Abstract:
This article describes advances in the knowledge of airborne infection in operating rooms since 1867 when Joseph Lister first provided methods of controlling surgical site infection. However, it was not until the mid-20th century that evidence became available to show that airborne microbes were a cause of surgical site infection, and the design of operating rooms was improved to control this route of infection. The contributions from various researchers who investigated the importance of airborne infection and the design of operating rooms are discussed. It was concluded that further progress is still required to fully control airborne infection in operating rooms.
Insights
Advances in understanding airborne infection in operating rooms since Lister
Area of Science:
- Medical Microbiology
- Hospital Infection Control
- Environmental Engineering
Background:
- Joseph Lister pioneered surgical site infection control in 1867.
- Mid-20th century research confirmed airborne microbes cause surgical site infections.
- Operating room design evolved to mitigate airborne contamination.
Purpose of the Study:
- To review historical advancements in controlling airborne infection in operating rooms.
- To discuss research contributions to understanding airborne pathogens and OR design.
- To assess the current state and future needs in operating room infection control.
Main Methods:
- Historical literature review of infection control practices.
- Analysis of research on airborne microbes and surgical site infections.
- Examination of operating room design evolution for infection prevention.
Main Results:
- Significant progress in controlling airborne infection since Lister's initial work.
- Established link between airborne microbes and surgical site infections.
- Ongoing challenges remain in fully eradicating airborne infection in operating rooms.
Conclusions:
- Continuous research and technological innovation are crucial for enhanced operating room safety.
- Further advancements are necessary to achieve complete control of airborne pathogens.
- A multidisciplinary approach is essential for future progress in operating room infection prevention.
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