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Updated: May 13, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

Complete genome sequence of the Streptococcus parauberis lytic bacteriophage JYU001

Young-Ung Heo1, Ju-Yeop Lee1, Hyo-Young Kang1

  • 1Department of Aquatic Life Medicine, College of Fisheries Sciences, Pukyong National University, Busan, South Korea.

Microbiology Resource Announcements
|May 12, 2026
PubMed

Insights

We sequenced the Streptococcus parauberis bacteriophage JYU001 genome. This lytic phage has a dsDNA genome encoding 69 proteins, with no detected virulence or resistance genes.

Area of Science:

  • Microbiology
  • Virology
  • Genomics

Background:

  • Bacteriophages are viruses that infect bacteria.
  • Streptococcus parauberis is a species of bacteria.
  • Understanding bacteriophage genomes is crucial for phage therapy and microbial ecology.

Purpose of the Study:

  • To report the complete genome sequence of Streptococcus parauberis bacteriophage JYU001.
  • To analyze the genomic features and predict the lifestyle of the phage.

Main Methods:

  • Whole genome sequencing of bacteriophage JYU001.
  • Bioinformatic analysis of the genome sequence, including CDS prediction.
  • Phylogenetic analysis and lifestyle prediction using PhaTYP.

Main Results:

  • The complete genome sequence of bacteriophage JYU001 was determined (36,295 bp dsDNA).
  • The genome encodes 69 predicted coding sequences (CDSs).
  • No tRNA genes, integrase genes, antimicrobial resistance genes, or virulence factors were detected; a lytic lifestyle was predicted.

Conclusions:

  • Bacteriophage JYU001 is a novel lytic phage infecting Streptococcus parauberis.
  • Its genome lacks genes associated with lysogeny, antimicrobial resistance, or virulence.
  • The genomic data provides insights into phage-host interactions and potential applications in phage therapy.
Keywords:
Streptococcus parauberisbacteriophage therapybacteriophages

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