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Updated: May 13, 2026

Vessel-sparing Excision and Primary Anastomosis
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Long-term (>5 Years) Outcomes after Magnetic Sphincter Augmentation.

Brian E Louie1, Henok G Woldu2, Reginald C W Bell3

  • 1Division of Thoracic Surgery, Swedish Medical Center, Seattle, WA.

Annals of Surgery
|May 12, 2026
PubMed
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This summary is machine-generated.

Magnetic sphincter augmentation (MSA) effectively manages gastroesophageal reflux disease (GERD) symptoms long-term, reducing reliance on proton pump inhibitors (PPIs). However, 13% of patients may require device explantation.

Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Medical Device Technology

Background:

  • Magnetic sphincter augmentation (MSA) is a recognized treatment for gastroesophageal reflux disease (GERD).
  • Short-term studies confirm MSA's efficacy, but long-term patient outcomes and objective data are essential.
  • Further long-term data are needed to fully support MSA's role in GERD management.

Purpose of the Study:

  • To evaluate the long-term (5-year) patient-reported outcomes of magnetic sphincter augmentation (MSA).
  • To assess objective measurements of GERD control via pH testing after MSA.
  • To determine the durability and safety profile of MSA over a 5-year period.

Main Methods:

  • A prospective FDA post-approval study included 200 patients with GERD unresponsive to acid suppression therapy.
Keywords:
LINXgastroesophageal reflux diseasemagnetic sphincter augmentationproton pump inhibitorsquality of life

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  • Patients underwent laparoscopic implantation of a magnetic sphincter device.
  • Clinical success was defined as a ≥50% improvement in GERD-health-related quality of life scores off proton pump inhibitors (PPIs) at 5-year follow-up.

    • Main Results:

    • 81.6% of 136 follow-up patients achieved ≥50% improvement in GERD-health-related quality of life scores.
    • 90.4% of patients achieved freedom from daily PPI use.
    • Objective measures showed significant reduction in % time pH <4 (9.1% to 3.2%) and DeMeester scores (29 to 11).

    Conclusions:

    • Magnetic sphincter augmentation (MSA) provides sustained control of GERD symptoms and reduces the need for PPIs.
    • While generally safe and effective, 13% of patients required device explantation, with most experiencing symptom resolution post-explantation.
    • MSA demonstrates a favorable long-term safety and efficacy profile for managing GERD.