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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Psychotherapy is a versatile, nonmedical approach aimed at helping individuals address emotional, behavioral, and interpersonal issues to enhance their overall well-being. It can involve one-on-one sessions, couples counseling, or small group discussions with a therapist. The therapeutic process includes various techniques such as open discussion, interpretation of thoughts and behaviors, active listening, positive reinforcement, and role modeling. Psychotherapy aims to support individuals in...
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Family therapy conceptualizes psychological challenges as arising from dysfunctional interactions within the family unit, rather than as isolated issues within individuals. This approach seeks to address and transform the patterns of communication, roles, and relationships within families to promote healthier dynamics and emotional well-being for all members.
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Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...

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Goal-directed therapy is not as simple as it seems.

Nelson B Watts1

  • 1Mercy Health Osteoporosis and Bone Health Services, 4760 East Galbraith Road, Suite 212, Cincinnati OH 45236.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|May 12, 2026
PubMed
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Postmenopausal osteoporosis treatment with alendronate may not always reach target bone mineral density (BMD) goals. This case highlights the need to reassess treatment effectiveness and consider alternative therapies for improved outcomes.

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Area of Science:

  • Geriatric Medicine
  • Pharmacology
  • Bone Metabolism

Background:

  • Osteoporosis is a common condition in postmenopausal women, increasing fracture risk.
  • Alendronate is a widely prescribed bisphosphonate for osteoporosis treatment.
  • Goal-directed therapy aims to achieve specific bone mineral density (BMD) targets.

Purpose of the Study:

  • To discuss a case of a postmenopausal woman undergoing alendronate treatment for osteoporosis.
  • To evaluate the effectiveness of alendronate in achieving target BMD at the total hip.
  • To explore treatment modification options when therapeutic goals are not met.

Main Methods:

  • Case report of a postmenopausal woman.
  • Monitoring of total hip bone mineral density (BMD) over three years.
  • Assessment against American Society for Bone and Mineral Research (ASBMR) task force guidelines.

Main Results:

  • The patient's total hip T-score remained below -2.5 after three years of alendronate treatment.
  • The established therapeutic target for goal-directed therapy was not achieved.

Conclusions:

  • Continued alendronate therapy may not be sufficient if BMD targets are not met.
  • Alternative osteoporosis treatments should be considered to improve total hip BMD.
  • Individualized treatment adjustments are crucial for effective osteoporosis management.