Related Experiment Video
Updated: May 14, 2026

04:47
Optimizing the Modified No-Scalpel Vasectomy Technique
Published on: October 18, 2024
Post Vasectomy Semen Analysis Completion in Clinic-Based Versus Mail-In Testing
Mark Doss1, Hunter Kraus2, Glendon Markollari2
1University of Missouri School of Medicine, Columbia, MO.
Urology
|May 12, 2026
Summary
Mail-in post-vasectomy semen analysis (PVSA) kits show comparable completion rates to clinic-based testing. Patient age and marital status, not testing method, are key factors for successful PVSA follow-up.
Area of Science:
- Urology
- Reproductive Health
- Public Health
Background:
- Post-vasectomy semen analysis (PVSA) is crucial for confirming vasectomy success.
- Traditional clinic-based PVSA may present logistical barriers for patients.
- Mail-in PVSA kits offer a potentially more accessible alternative.
Purpose of the Study:
- To compare post-vasectomy semen analysis (PVSA) completion rates between clinic-based and mail-in testing methods.
- To evaluate the impact of a protocol change on PVSA completion.
- To identify factors influencing PVSA adherence.
Main Methods:
- Retrospective review of 966 patients undergoing vasectomy (January 2015-September 2023).
- Comparison of PVSA completion rates (within 6 months and overall) between clinic-based and mail-in groups.
- Statistical analysis using chi-squared tests, t-tests, odds ratios, and multivariable logistic regression.
Main Results:
- Significantly higher PVSA completion within six months for the mail-in group (83.42% vs 77.7%).
- No significant difference in overall PVSA completion rates between mail-in and clinic-based groups (80.57% vs 84.49%).
- Patient age and marital status were independently associated with PVSA completion in multivariable analysis.
Conclusions:
- Mail-in PVSA demonstrates comparable adherence to clinic-based methods.
- Testing modality is less influential on completion than patient age and marital status.
- Mail-in PVSA is a viable and effective option for post-vasectomy follow-up.

