Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Atomic Nuclei: Nuclear Relaxation Processes01:23

Atomic Nuclei: Nuclear Relaxation Processes

In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis. This...
NMR Spectrometers: Overview01:20

NMR Spectrometers: Overview

NMR spectrometers consist of a strong magnet, a radiofrequency transmitter, and a detector attached to a computer console for recording spectra of samples containing NMR-active nuclei. In first-generation NMR instruments called continuous-wave spectrometers, the resonance frequencies of the nuclei are determined by frequency-sweep or field-sweep methods. The magnetic field strength is fixed and the rf signal is swept in the former, while the radiofrequency signal is fixed and the magnetic field...
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences01:17

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary Radiation Damage in a Strain-Engineering-Based SiGe/Si Heterostructure: A Molecular Dynamics Simulation.

Nanomaterials (Basel, Switzerland)·2026
Same author

Rapid atomic-signal-based in-situ magnetic compensation for unshielded spin-exchange relaxation-free atomic magnetometer.

The Review of scientific instruments·2026
Same author

An Explainable Molecular Token Estimation Method for Knowledge-Aware Drug-Drug Interaction Prediction.

IEEE journal of biomedical and health informatics·2026
Same author

Letter to the editor: Proposal of a novel model for identifying complete response and nonoperative management in DMMR colon cancer following neoadjuvant immunotherapy: a retrospective cohort study.

International journal of surgery (London, England)·2025
Same author

Experimental investigation of wavelength-selective optical feedback for a high-power quantum dot superluminescent device with two-section structure.

Optics express·2012
Same author

A high-performance quantum dot superluminescent diode with a two-section structure.

Nanoscale research letters·2011

Related Experiment Video

Updated: May 14, 2026

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

Fiber-Coupled Fully Integrated Spin-Exchange Relaxation-Free Atomic Magnetometer for Functional Biomagnetic

Wennuo Jiang1, Jianjun Li2, Xinkun Li3

  • 1College of Optical Science and Engineering, Zhejiang University, Hangzhou 310027, China.

Sensors (Basel, Switzerland)
|May 13, 2026
PubMed
Summary
This summary is machine-generated.

A new atomic magnetometer (AM) offers ultrahigh sensitivity for biomagnetic measurements. This compact, integrated system shows potential for magnetocardiography and magnetoencephalography applications.

Keywords:
atomic magnetometerbiomagnetic measurementsfully integratedspin-exchange relaxation-free

More Related Videos

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
07:42

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

Published on: July 20, 2022

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
10:23

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Published on: December 13, 2016

Related Experiment Videos

Last Updated: May 14, 2026

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
07:42

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

Published on: July 20, 2022

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
10:23

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Published on: December 13, 2016

Area of Science:

  • Physics
  • Biomedical Engineering
  • Instrumentation

Background:

  • Atomic magnetometers (AMs) operating in the spin-exchange relaxation-free (SERF) regime offer superior sensitivity and resolution.
  • SERF AMs are a promising alternative to superconducting quantum interference devices for biomagnetic measurements.
  • Existing systems often lack full integration and compactness required for widespread clinical use.

Purpose of the Study:

  • To develop a fully integrated, compact SERF atomic magnetometer system.
  • To achieve high sensitivity and bandwidth suitable for magnetocardiography (MCG) and magnetoencephalography (MEG).
  • To demonstrate the system's capability in recording typical biomagnetic signals.

Main Methods:

  • Development of a compact sensor head using a 4 mm cubic vapor cell and a single-beam scheme with polarization-maintaining fiber.
  • Integration of in-house control electronics, including laser driver, coil driver, temperature controller, and transimpedance amplifier.
  • Characterization of the system's sensitivity and bandwidth.

Main Results:

  • Achieved a sensitivity of 25 fT/Hz^1/2 at 5–100 Hz with a bandwidth of 193 Hz.
  • Successfully recorded typical magnetocardiography (MCG) and alpha rhythm magnetoencephalography (MEG) signals.
  • Demonstrated a fully integrated SERF AM system within a 9 cm^3 volume.

Conclusions:

  • The developed fully integrated SERF AM system meets the criteria for MCG and MEG.
  • The compact and sensitive system shows significant potential for advanced biomagnetic imaging.
  • This technology offers a promising pathway for next-generation non-invasive neuroimaging and cardiac diagnostics.