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White Tea Modulates Metabolic Parameters and Adipokine Signaling in Experimental Obesity: Evidence for Functional
Ayşegül Sümer1, Öznur Demirtaş1, Esra Pınarbaş Kanbur1
1Department of Medical Biochemistry, Faculty of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Türkiye.
Abstract:
Functional foods enriched with bioactive compounds have attracted increasing attention for their potential to improve metabolic health and reduce the risk of chronic diseases. White tea, a minimally processed tea rich in polyphenols and antioxidant constituents, may exert beneficial effects on obesity-related metabolic disturbances through multiple molecular pathways. In this study, we investigated the effects of white tea in a high-fat diet-induced obesity model in rats, with particular emphasis on metabolic regulation and adipokine signaling. Body weight, lipid profile, glucose homeostasis, insulin resistance-related parameters, and circulating levels of apelin and irisin were evaluated. High-fat diet feeding impaired metabolic balance and altered obesity-associated biochemical parameters, whereas white tea administration ameliorated several of these changes. White tea was associated with improvements in body weight gain and selected metabolic parameters, together with modulation of adipokine-related markers. These findings suggest that white tea may function as a bioactive-rich functional food with beneficial effects on pathways involved in obesity and metabolic homeostasis. Our results support the potential contribution of white tea-derived compounds to nutrition-based strategies for the prevention and management of obesity.
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