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Epistaxis

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
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Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...

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Related Experiment Video

Updated: May 14, 2026

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

Persistent Epithelial Defect After Bullae Rupture With Netarsudil.

Tarannum Mansoori¹

¹Ophthalmology, Prime Retina Eye Care Center, Hyderabad, IND.

|May 13, 2026

Summary

This summary is machine-generated.

Topical netarsudil 0.02% may cause recurrent reticular epithelial edema (REE) and bullae, potentially leading to persistent epithelial defects. Ophthalmologists should monitor for these corneal adverse effects and manage accordingly.

Area of Science:

Ophthalmology
Corneal Disease
Pharmacology

Background:

Topical netarsudil is a Rho-kinase inhibitor used for glaucoma treatment.

Keywords:

corneal bullae glaucoma netarsudil eye drop persistent epithelial defect reticular epithelial edema

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Reticular epithelial edema (REE) and bullae are potential ocular side effects.

Understanding netarsudil's corneal toxicity is crucial for patient safety.