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Related Experiment Video

Updated: May 15, 2026

Demystifying Venous Excess Ultrasound (VExUS): Image Acquisition and Interpretation

Demystifying Venous Excess Ultrasound (VExUS): Image Acquisition and Interpretation

Published on: May 16, 2025

'Not All Swellings Are Angioedema' - An Overview And Systematic Approach For Acute Medical Physicians.

Kavitha Sooriyakumar¹, Sahar Ahmed², Leman Mutlu¹

¹Department of Allergy and Immunology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

|May 13, 2026

Summary

Angioedema, a localized swelling, is often misdiagnosed in emergency rooms. This review clarifies angioedema hallmarks and mimics to improve diagnostic accuracy for healthcare professionals.

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Last Updated: May 15, 2026

Demystifying Venous Excess Ultrasound (VExUS): Image Acquisition and Interpretation

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Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

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Published on: July 28, 2018

Area of Science:

Clinical Medicine
Emergency Medicine
Dermatology

Background:

Angioedema is localized swelling of subcutaneous and submucosal tissues.
It results from vasoactive peptide release (histamine, bradykinin).
Diagnosis can be challenging in emergency settings due to similar presentations.

Purpose of the Study:

To provide an overview of angioedema hallmarks and etiology.
To discuss conditions that mimic angioedema, leading to misdiagnosis.
To highlight key features for differentiating angioedema from its mimics.

Main Methods:

Literature review of angioedema diagnosis and differential diagnoses.
Analysis of typical angioedema characteristics.
Case study review of misdiagnosed angioedema cases.

Main Results:

Angioedema diagnosis is complicated by numerous mucocutaneous swelling mimics.
Distinguishing features are crucial for accurate diagnosis.
Two cases illustrate common misdiagnoses.

Conclusions:

Accurate diagnosis of angioedema requires understanding its typical presentation and differentiating it from mimics.
Improved diagnostic skills can prevent misdiagnosis and ensure appropriate patient management.
Further education on angioedema and its mimics is warranted for healthcare professionals.