Time is muscle, context is key: Re-evaluating the urgency of aVR ST elevation

Federico Paolini1, Leonardo Brugiatelli1, Alessandro D'Alfonso2

  • 1Cardiology-UTIC, AST Pesaro, Italy.

Insights

The electrocardiogram (ECG) finding of ST elevation in lead aVR with diffuse ST depression can indicate serious cardiac issues. This case highlights its association with type A aortic dissection, not just coronary artery disease.

Area of Science:

  • Cardiology
  • Emergency Medicine
  • Diagnostic Imaging

Background:

  • ST-segment elevation in lead aVR with diffuse ST depression is a recognized ECG pattern.
  • This pattern is traditionally linked to acute coronary syndromes, specifically left main or three-vessel coronary artery disease.
  • However, the diagnostic specificity of this ECG finding remains debated.

Purpose of the Study:

  • To report a case where the characteristic ECG pattern was associated with type A aortic dissection.
  • To emphasize the importance of considering differential diagnoses in patients with hemodynamic instability presenting with this ECG pattern.

Main Methods:

  • Case report of a 60-year-old male with chest pain and hemodynamic shock.
  • Electrocardiogram (ECG) interpretation revealing diffuse ST depression and ST elevation in lead aVR.
  • Physical examination and echocardiography leading to suspicion of type A aortic dissection.
  • Computed tomography (CT) scan confirming the diagnosis of type A aortic dissection.

Main Results:

  • The patient presented with symptoms suggestive of acute coronary syndrome.
  • The ECG findings prompted urgent cardiac catheterization.
  • Diagnosis was ultimately type A aortic dissection, not coronary artery disease.
  • This highlights the critical need for differential diagnosis.

Conclusions:

  • The ECG pattern of ST elevation in lead aVR with diffuse ST depression is not exclusive to coronary artery disease.
  • In patients with hemodynamic instability, this ECG finding necessitates a broad differential diagnosis.
  • Type A aortic dissection should be considered in the differential diagnosis for this ECG presentation.

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