[Research progress and clinical practice considerations on assessment tools for gastroesophageal reflux disease in

Ruo-Xin Liu1, Rong-Hua Li1, Cai-Xin Yin

  • 1Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou 510623, China.

Insights

Gastroesophageal reflux disease (GERD) in children is hard to diagnose. The Infant Gastroesophageal Reflux Questionnaire-Revised (I-GERQ-R) is recommended for assessing GERD symptoms and treatment response.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Assessment Tools
  • Digestive Disorders

Background:

  • Gastroesophageal reflux disease (GERD) in infants and young children presents diagnostic challenges due to overlapping symptoms with physiological reflux.
  • Effective management requires accurate identification and assessment of GERD in pediatric populations.

Purpose of the Study:

  • To review epidemiological characteristics, clinical presentations, and impacts of GERD in children.
  • To appraise the development, reliability, validity, and clinical utility of four key GERD assessment tools for infants and young children.
  • To support early identification, standardized assessment, and individualized management of pediatric GERD.

Main Methods:

  • Conducted comprehensive literature searches in English and Chinese databases (PubMed, Web of Science, CNKI, Wanfang Data).
  • Focused on reviewing epidemiological data, clinical manifestations, and the impact of GERD on children and families.
  • Critically evaluated four principal assessment tools: I-GERQ, GSQ-I/YC, I-GERQ-R, and GIGER.

Main Results:

  • The Infant Gastroesophageal Reflux Questionnaire-Revised (I-GERQ-R) demonstrates high specificity, reliability, validity, and cross-cultural applicability.
  • The I-GERQ-R is recommended for symptom assessment and monitoring treatment response in pediatric GERD.
  • The Gastrointestinal and Gastroesophageal Reflux Scale for Infants and Toddlers (GIGER) shows potential for comprehensive screening.

Conclusions:

  • The I-GERQ-R is a valuable tool for assessing GERD in infants and young children.
  • The GIGER scale offers promise for broader GERD screening applications.
  • Future research should focus on developing Chinese versions of GERD questionnaires and establishing multidimensional assessment systems for pediatric GERD.

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