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Updated: May 15, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
[Research progress and clinical practice considerations on assessment tools for gastroesophageal reflux disease in
Ruo-Xin Liu1, Rong-Hua Li1, Cai-Xin Yin
1Women and Children's Medical Center Affiliated to Guangzhou Medical University, Guangzhou 510623, China.
Insights
Gastroesophageal reflux disease (GERD) in children is hard to diagnose. The Infant Gastroesophageal Reflux Questionnaire-Revised (I-GERQ-R) is recommended for assessing GERD symptoms and treatment response.
Area of Science:
- Pediatric Gastroenterology
- Clinical Assessment Tools
- Digestive Disorders
Background:
- Gastroesophageal reflux disease (GERD) in infants and young children presents diagnostic challenges due to overlapping symptoms with physiological reflux.
- Effective management requires accurate identification and assessment of GERD in pediatric populations.
Purpose of the Study:
- To review epidemiological characteristics, clinical presentations, and impacts of GERD in children.
- To appraise the development, reliability, validity, and clinical utility of four key GERD assessment tools for infants and young children.
- To support early identification, standardized assessment, and individualized management of pediatric GERD.
Main Methods:
- Conducted comprehensive literature searches in English and Chinese databases (PubMed, Web of Science, CNKI, Wanfang Data).
- Focused on reviewing epidemiological data, clinical manifestations, and the impact of GERD on children and families.
- Critically evaluated four principal assessment tools: I-GERQ, GSQ-I/YC, I-GERQ-R, and GIGER.
Main Results:
- The Infant Gastroesophageal Reflux Questionnaire-Revised (I-GERQ-R) demonstrates high specificity, reliability, validity, and cross-cultural applicability.
- The I-GERQ-R is recommended for symptom assessment and monitoring treatment response in pediatric GERD.
- The Gastrointestinal and Gastroesophageal Reflux Scale for Infants and Toddlers (GIGER) shows potential for comprehensive screening.
Conclusions:
- The I-GERQ-R is a valuable tool for assessing GERD in infants and young children.
- The GIGER scale offers promise for broader GERD screening applications.
- Future research should focus on developing Chinese versions of GERD questionnaires and establishing multidimensional assessment systems for pediatric GERD.
Abstract:
Gastroesophageal reflux disease (GERD) in infants and young children is a common digestive disorder with diverse clinical manifestations that often overlap with physiological reflux and behavioral expressions, creating diagnostic challenges. Comprehensive searches were conducted in English- and Chinese-language databases, including PubMed, Web of Science, China National Knowledge Infrastructure, and Wanfang Data, to review the epidemiological characteristics, clinical presentations, and impacts of GERD on children and their families. Particular emphasis is placed on four principal assessment tools [Infant Gastroesophageal Reflux Questionnaire (I-GERQ), GERD Symptom Questionnaire for Infants/Young Children (GSQ-I/YC), I-GERQ Revised (I-GERQ-R), and Gastrointestinal and Gastroesophageal Reflux Scale for Infants and Toddlers (GIGER)], appraising their development background, structural characteristics, reliability, validity, and clinical application value. The aim is to support early identification, standardized assessment, and individualized management of GERD in infants and young children. Evidence indicates that the I-GERQ-R shows high specificity, good reliability and validity, and cross-cultural applicability, and is currently recommended for symptom assessment and treatment-response monitoring in GERD among infants and young children, while the GIGER scale shows potential for comprehensive screening. Future research should prioritize translation and development of Chinese versions of GERD questionnaires for infants and young children, as well as the establishment of a multidimensional assessment system.
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