Related Experiment Video
Updated: May 15, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
Published on: January 5, 2024
Efficacy of Combined Music and Cryotherapy for Pain Relief During Mediastinal Drain Removal After Myocardial
Thatiane Evelyn de Lima Fernandes1, Kauanny Vitória Gurgel Dos Santos1, José Joandson de Souza Dos Santos1
1Federal University of Rio Grande do Norte, Natal, Brazil.
Insights
This study investigates music therapy and cryotherapy for pain relief during mediastinal drain removal after heart surgery. These non-pharmacological methods aim to reduce patient discomfort and opioid use.
Area of Science:
- Cardiology
- Pain Management
- Integrative Health Practices
Background:
- Coronary artery bypass grafting (CABG) necessitates mediastinal drains, and their removal is a painful experience.
- Effective pain management is crucial to minimize opioid exposure and adverse effects.
- Non-pharmacological strategies like music therapy and cryotherapy show promise for pain and anxiety reduction.
Purpose of the Study:
- To evaluate the combined efficacy of music therapy and cryotherapy in reducing pain during mediastinal drain removal.
- To assess the impact of these interventions on patients undergoing myocardial revascularization surgery.
Main Methods:
- A randomized clinical trial adhering to SPIRIT and CONSORT guidelines.
- 52 participants will be allocated to an experimental group (music therapy + cryotherapy) or a control group (standard care).
- Pain intensity will be measured using the Numerical Rating Scale (NRS).
Main Results:
- The study is designed to measure the reduction in pain intensity.
- Feasibility will be assessed via a pilot test.
- Results will provide data on the effectiveness of combined music and cryotherapy.
Conclusions:
- This research aims to contribute novel evidence on integrative and complementary health practices.
- The findings are expected to optimize post-myocardial revascularization care.
- The study seeks to enhance patient outcomes through non-pharmacological pain management.
Introduction:
Coronary artery bypass grafting (CABG) is a procedure that requires the use of a mediastinal drain to prevent blood accumulation around the heart. Removal of this device is recognized as a painful experience for the patient. In this context, the adoption of cost-effective, non-pharmacological pain management strategies is essential to reduce adverse effects and minimize opioid exposure. Among these strategies, music-based intervention and cryotherapy emerge as promising interventions, supported by scientific evidence indicating their efficacy in reducing pain and anxiety.
Objective:
To evaluate the efficacy of the combined use of music and cryotherapy in alleviating pain during mediastinal drain removal in patients undergoing myocardial revascularization surgery.
Methodology:
This is a randomized clinical trial, developed in accordance with the SPIRIT and CONSORT guidelines. The primary outcome of the study is the reduction in pain intensity, as measured by the established Numerical Rating Scale (NRS). The study will be conducted in the Intensive Care Unit of the Heart Hospital of Natal, involving two groups: the experimental group, which will receive the music-based intervention and cryotherapy, and the control group, which will follow the institution's standard care. The sample will consist of 52 randomly allocated participants, and feasibility will be evaluated through a pilot test with the first five. Eligibility criteria include: age ≥18 years, postoperative hemodynamic stability, a score of 15 on the Glasgow Coma Scale, ability to understand and respond to pain assessment instruments, and the presence of a mediastinal drain scheduled for removal.
Conclusion:
This study aims to contribute new evidence regarding integrative and complementary health practices, thereby optimizing the comprehensive care delivered to patients post-myocardial revascularization.
Registration:
This study is registered on the Brazilian Registry of Clinical Trials (ReBEC) platform under the number RBR-2nzh9vr and was approved by the Research Ethics Committee of the Federal University of Rio Grande do Norte (Opinion no. 83976124.0.0000.5537).
Related Concept Videos
Mitral Regurgitation III: Medical Management
Pericarditis III: Medical Management
Myocarditis III: Medical Management
Mitral Stenosis III: Medical Management