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Related Concept Videos

Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

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Updated: May 16, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Pulmonary vascular changes after lung resection: why less may be more.

Valentin Bovy1, Patrick Alexander2

  • 1Catholic University of Leuven, Leuven, Belgium. valentinbovy1504@gmail.com.

General Thoracic and Cardiovascular Surgery
|May 14, 2026
PubMed
Summary

Lung resection surgery, like lobectomy and segmentectomy, impacts pulmonary hemodynamics. Segmentectomy may offer better survival and less vascular impact than lobectomy for select lung cancers.

Keywords:
Pulmonary hypertensionLobectomyLung resectionPneumonectomySegmentectomy

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Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices
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Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices

Published on: January 14, 2014

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Last Updated: May 16, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
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Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices
13:32

Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices

Published on: January 14, 2014

Area of Science:

  • Thoracic surgery
  • Cardiopulmonary physiology
  • Surgical oncology

Background:

  • Pneumonectomy, a major lung resection, has high mortality (7%), leading to its replacement by less invasive procedures.
  • Lobectomy, widely used since the mid-20th century, has lower mortality but significant cardiorespiratory morbidity, including exercise intolerance and pulmonary hypertension.
  • Segmentectomy, a lung-sparing approach, is gaining traction for early-stage non-small cell lung cancer, potentially offering survival benefits.

Purpose of the Study:

  • To review the literature on the effects of different lung resection types on pulmonary vasculature.
  • To explore the pathophysiological mechanisms behind these vascular changes.

Main Methods:

  • Literature review of studies on pneumonectomy, lobectomy, and segmentectomy.
  • Analysis of data on pulmonary hemodynamics and cardiorespiratory morbidity following lung resection.

Main Results:

  • Lobectomy is associated with significant pulmonary vascular changes and reduced exercise capacity.
  • Segmentectomy, by removing less lung tissue, is hypothesized to have a more limited impact on pulmonary vasculature.
  • Carefully selected patients may experience better survival with segmentectomy compared to lobectomy.

Conclusions:

  • Lung resection type significantly influences pulmonary hemodynamics and cardiorespiratory outcomes.
  • Segmentectomy represents a potentially less impactful alternative to lobectomy for specific lung cancer cases.
  • Further research is needed to fully elucidate the long-term vascular effects of different lung resection techniques.