Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sex- and Age-Dependent Outcomes of Cryoablation in Atrial Fibrillation: A 3- and 6-Month Post-Procedural QoL Analysis.

Journal of arrhythmia·2026
Same authorSame journal

Mast Cells and Cardiovascular Disorders.

Current vascular pharmacology·2026
Same authorSame journal

Occupational and Environment-Related Cardiovascular Disease: A Comprehensive Review of the Literature.

Current vascular pharmacology·2026
Same author

The Kallikrein-Kinin System and Cardiovascular Diseases: A Narrative Review.

Angiology·2026
Same authorSame journal

The Use of Colchicine in Cardiovascular Disease: Anti-Inflammatory Mechanisms and Clinical Utility.

Current vascular pharmacology·2026
Same author

Ascending Aorta Aneurysm: What the Cardiologist Needs to Know.

Angiology·2026
Same journal

Metalloproteinases 2 and 9 as Biomarkers in Acute Elevation of Blood Pressure.

Current vascular pharmacology·2026
Same journal

Is the Cardiovascular Risk Increased in Patients with Isolated Systolic Hypertension and Anemia?

Current vascular pharmacology·2026
Same journal

Chitosan-Saponin-Bentonite Nanocomposites Prevent Doxorubicin-Induced Cardiovascular Toxicity by Inhibiting Oxidative Stress and Apoptosis.

Current vascular pharmacology·2026
See all related articles

Related Experiment Videos

Periodontal Disease and Cardiovascular Risk Factors.

Antonis A Manolis1, Theodora A Manolis2, Antonis S Manolis3

  • 1Department of Medicine, Elpis General Hospital, Athens, Greece.

Current Vascular Pharmacology
|May 15, 2026
PubMed
Summary
This summary is machine-generated.

Periodontal disease, an oral infection, is linked to numerous systemic health issues like cardiovascular disease. Managing this gum condition can improve overall and cardiovascular health, highlighting the importance of integrated dental and medical care.

Keywords:
Periodontal diseasecardiovascular diseasecardiovascular healthchronic kidney diseasediabetesgingivitis.hypertensioninflammationobesityoxidative stressperiodontitissmoking

Related Experiment Videos

Area of Science:

  • Oral Health and Systemic Disease
  • Periodontology
  • Cardiovascular Health

Background:

  • Periodontitis affects 7-11% of adults globally, presenting local symptoms like gingival inflammation and bone loss.
  • Emerging evidence links periodontitis to systemic conditions including obesity, diabetes, cardiovascular disease (CVD), and autoimmune disorders.
  • The association between periodontal disease and systemic health is bidirectional.

Purpose of the Study:

  • To explore the links between periodontal disease and systemic health conditions.
  • To elucidate the mechanisms mediating these associations.
  • To emphasize the importance of managing periodontitis for overall health outcomes.

Main Methods:

  • Review of existing studies on periodontal disease and systemic health.
  • Identification of key pathogenic mechanisms.
  • Analysis of the impact of periodontitis management on systemic conditions.

Main Results:

  • Periodontitis is associated with systemic conditions via dysbiotic oral biofilms, systemic inflammation, and microbial spread.
  • Pathophysiological mechanisms include pro-inflammatory cytokines, C-reactive protein, impaired immunity, and oxidative stress.
  • Management of periodontitis has shown improvements in associated systemic conditions.

Conclusions:

  • Periodontitis significantly contributes to systemic inflammation, impacting general and cardiovascular health.
  • A multidisciplinary approach to periodontal disease management is crucial for improving patient outcomes.
  • Oral health is an integral component of systemic health, requiring integrated healthcare provider attention.