Ocular Surgery in Patients With Severe Atherosclerotic Disease: Anesthetic Considerations and Vascular Risk

Saul J Prado Fonseca1, Fabiana M Araya Padilla1, Nicole Rodríguez2

  • 1Emergency Medicine, Hospital Monseñor Sanabria Martínez, Puntarenas, CRI.

Cureus
|May 15, 2026
PubMed

Insights

Ocular surgery in patients with severe atherosclerotic disease poses risks due to compromised vascular health. Comprehensive preoperative evaluation and individualized perioperative management are crucial for optimizing safety and outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Ophthalmology
  • Vascular Surgery

Background:

  • Severe atherosclerotic disease presents challenges for ocular surgery due to compromised vascular autoregulation and reduced ocular perfusion.
  • Aging populations increase the prevalence of cardiovascular comorbidities, elevating risks for ophthalmic procedures, including cataract surgery.
  • Atherosclerosis-related endothelial dysfunction, inflammation, and arterial stiffness heighten susceptibility to perioperative ischemic complications.

Purpose of the Study:

  • To outline a comprehensive preoperative evaluation strategy for patients undergoing ocular surgery with severe atherosclerotic disease.
  • To detail perioperative management considerations, including anesthetic techniques and hemodynamic monitoring.
  • To emphasize the importance of a multidisciplinary approach for optimizing outcomes in this high-risk population.

Main Methods:

  • Comprehensive preoperative assessment including cardiovascular history, functional capacity, and frailty evaluation.
  • Utilizing risk indices and targeted investigations like ECG, echocardiography, and carotid Doppler imaging.
  • Individualized management of antithrombotic therapy and selection of appropriate anesthetic techniques (topical, Sub-Tenon block, or general anesthesia).

Main Results:

  • Preoperative evaluation identifies high-risk features and guides perioperative planning.
  • Anesthetic technique choice significantly impacts hemodynamic stability.
  • Intraoperative strategies focus on maintaining stable mean arterial pressure, avoiding extreme blood pressure variations, and ensuring normocapnia.
  • Postoperative care involves monitoring for ischemia, arrhythmias, and neurological events, with timely resumption of antithrombotic therapy.

Conclusions:

  • A multidisciplinary and individualized approach is essential for optimizing perioperative safety in patients with severe atherosclerotic disease undergoing ocular surgery.
  • Careful preoperative assessment, tailored anesthetic choices, and vigilant intraoperative/postoperative monitoring are key to mitigating risks.
  • Effective management balances thrombotic and bleeding risks, particularly concerning antithrombotic therapy, to improve patient outcomes.

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...