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Updated: May 17, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
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Published on: September 12, 2025

Successful Perioperative Management of Pregnancy-Related Acquired Hemophilia A Using Only Bypassing Agents: A Case

Mai Yamamoto1, Harunori Muraoka, Takahiro Suzuki

  • 1From the Department of Anesthesiology, Nihon University School of Medicine, Tokyo, Japan.

A&A Practice
|May 15, 2026
PubMed

We report a confirmed case of pregnancy-associated acquired hemophilia A identified during preoperative evaluation for cesarean delivery. Although immunosuppressive therapy is generally recommended to eradicate factor VIII inhibitors, urgent delivery was required because of pregnancy-induced hypertension complicated by nephropathy. Under these circumstances, a cesarean delivery was performed without previous immunosuppressive treatment. Intraoperative hemostasis was well controlled, and both maternal and neonatal outcomes were favorable. This report may assist in clinical decision-making when invasive procedures are required in patients with acquired hemophilia A before therapeutic intervention with immunosuppressive therapy can be initiated.

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