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Updated: May 17, 2026
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A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
Published on: December 26, 2016
Prognostic factors for breast cancer progression
Yulia Chuprovska1, Volodymyr Bodiaka1, Oleksandr Ivashchuk1
1BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE.
Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|May 15, 2026
Summary
This study identifies key factors influencing breast cancer progression after treatment, aiding in predicting outcomes for patients with different tumor types and stages. A prognostic model shows 75% sensitivity and specificity for predicting progression.
Area of Science:
- Oncology
- Clinical Research
Background:
- Breast cancer is a complex disease with varied progression patterns.
- Understanding factors influencing tumor progression post-treatment is crucial for patient management.
Purpose of the Study:
- To analyze clinical and laboratory features of breast cancer progression.
- To evaluate the impact of disease stage and molecular tumor type on progression.
- To determine the prognostic value of various factors in breast cancer.
Main Methods:
- Retrospective analysis of 701 breast cancer patient records.
- Patients categorized into 'without tumor progression' (67.3%) and 'with tumor progression' (32.7%) groups.
- Kullback method used to assess indicator informativeness; statistical analysis via Microsoft Excel and PAST software.
Main Results:
- Tumor progression is more frequent in Stage III, Luminal B, HER2-positive, and Triple-negative breast cancers.
- Progression correlates with longer disease history, larger primary tumors, and increased comorbidities.
- A prognostic table for breast cancer progression after complex treatment was developed.
Conclusions:
- A prognostic model for breast cancer progression was established.
- The model predicts absence of progression, uncertain prognosis, and progression with 75% sensitivity and 75% specificity.
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