Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 17, 2026

Demonstration of Spin-Multiplexed and Direction-Multiplexed All-Dielectric Visible Metaholograms
08:48

Demonstration of Spin-Multiplexed and Direction-Multiplexed All-Dielectric Visible Metaholograms

Published on: September 25, 2020

High-Dimensional Diagnostic Encoding with Out-of-Plane Nonlocal Metasurfaces.

Jiacheng Sun1,2,3, Fajun Li4,5, Sisi Yan2,3

  • 1College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.

Nano Letters
|May 15, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endowing Metal Oxychloride Solid Electrolytes with Improved Li Compatibility.

Journal of the American Chemical Society·2026
Same author

Trajectories of quality of life in pancreatic cancer survivors during the first year after surgery: a longitudinal study.

Scientific reports·2026
Same author

A self-powered spherical compound eye with 8 ns-motion response for source-constrained drones.

Nature communications·2026
Same author

Layered Graphene/Hydrogel-Based Multi-Modal Sensors Enabled by Ion-Electron Synergistic Conduction.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

RAD18 facilitates cancer progression and immunosuppression via the AKT/mTOR/c-Myc axis: a multi-omics analysis.

NPJ precision oncology·2026
Same author

Clinicopathological and molecular characteristics associated with pathological complete response in neoadjuvant immunotherapy for breast cancer.

Frontiers in immunology·2026
Same journal

Spider-Silk-Like Single-Fiber Actuators with Two Actuation Modes Driven by Water.

Nano letters·2026
Same journal

Clicking 1,4-Dithiin Conjugated Dimaleimides for Chiroptical Evolution and Nanofabrication.

Nano letters·2026
Same journal

Dynamic Quantum Gate Based on Controllable Chiral Liquid Crystal Nanostructure.

Nano letters·2026
Same journal

Activating Phase-Transition Toughening in van der Waals Semiconductor GaTe.

Nano letters·2026
Same journal

Dual-Mode Nucleation and Dynamic Alloying of Silicon on Ag(111).

Nano letters·2026
Same journal

Surface-Neutralized HgCdSe Quantum Dots for High-Detectivity Infrared Photodetectors.

Nano letters·2026
See all related articles
This summary is machine-generated.

This study introduces an out-of-plane nonlocal metasurface for advanced AI-assisted optical diagnosis. This novel biosensor enhances diagnostic accuracy by encoding rich spectral data, improving detection in complex samples.

Area of Science:

  • Nanophotonics
  • Biosensing
  • Artificial Intelligence

Background:

  • AI-assisted optical diagnosis needs reproducible spectral features.
  • Current nanophotonic biosensors often simplify complex optical responses to single scalar values.
  • This simplification limits diagnostic information and accuracy.

Purpose of the Study:

  • To develop a nanophotonic biosensor for robust, high-dimensional diagnostic encoding.
  • To improve AI-assisted diagnostic accuracy using full-spectrum analysis.
  • To overcome limitations of scalar observables in biosensing.

Main Methods:

  • Designed an out-of-plane nonlocal metasurface.
  • Utilized nonlocal lattice resonance for spectral-intensity variations.
  • Employed deep neural networks for full-spectrum response decoding.
Keywords:
AI-assisted diagnosisdefect-tolerant refractometric biosensingfull-spectrum diagnostic encodinghigh-dimensional spectral analysisout-of-plane nonlocal metasurface

More Related Videos

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces
09:33

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces

Published on: June 7, 2019

Related Experiment Videos

Last Updated: May 17, 2026

Demonstration of Spin-Multiplexed and Direction-Multiplexed All-Dielectric Visible Metaholograms
08:48

Demonstration of Spin-Multiplexed and Direction-Multiplexed All-Dielectric Visible Metaholograms

Published on: September 25, 2020

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces
09:33

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces

Published on: June 7, 2019

  • Assessed disorder tolerance and interference suppression.

    • Main Results:

    • The metasurface demonstrated high-dimensional encoding with strong disorder tolerance (0.1 nm/nm sensitivity).
    • Out-of-plane geometry reduced interference from complex liquids.
    • AI decoding of full-spectrum response improved diagnostic accuracy from ~75% to 90.0% (AUC 95.0%).

    Conclusions:

    • Out-of-plane nonlocal metasurfaces enable high-dimensional spectral encoding for biosensing.
    • This approach significantly enhances AI-assisted diagnostic decoding accuracy.
    • The technology shows promise for analyzing complex biological samples like serum.