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Updated: May 18, 2026

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines
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Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines

Published on: November 13, 2021

Re-balancing immunity with CRISPR-Cas9: Novel strategies for cancer and autoimmune disorders

Xuanqi Ren1, Ziyang Zhou1, Lingkai Kong2

  • 1Jinan Microecological Biomedicine Shandong Laboratory, Building 1, Jinan Medical and Health Science and Technology Innovation Industrial Park, No. 288, Jiqi Road, Huayin District, Jinan City, Shandong Province, China; State Key Laboratory of Pharmaceutical Biotechnology, Suqian Scientific Research Institute of Nanjing University Medical School, Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital, the Affiliated Hospital of Medical School, Medical School, Nanjing University, Nanjing 210008, China; "Nanjing University-Gulou" Joint Laboratory of AI and Healthcare BigData, National Institute of Healthcare Data Science at Nanjing University, School of Life Sciences, Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing 210093, China.

Biotechnology Advances
|May 16, 2026
PubMed

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Autoimmune diseaseCRISPR-Cas9Genome editingImmuneImmune toleranceImmunityImmunotherapyTumorTumor microenvironmentcancer