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Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer
Published on: November 15, 2024
Special Population: A Global Perspective on Metabolic Dysfunction-Associated Alcohol-Related Liver Disease
Winston Dunn1, Aleksander Krag2, Patrick Kamath3
1Department of Medicine, Gastroenterology Hepatology Division, Kansas University Medical Center, Kansas City, KS, USA.
None:
The nomenclature of steatotic liver disease advanced our understanding of the interplay between alcohol and cardiometabolic risk factors. The new nomenclature introduced a new entity of metabolic dysfunction and alcohol-associated liver disease or metabolic dysfunction-associated alcohol-related liver disease (MetALD). This brought in challenges like granular self-reported quantification on self-reported alcohol use and changing disease states due to dynamic alcohol use, with risk of misclassification of alcohol use. Given a worldwide increasing prevalence of metabolic syndrome and of alcohol use, this article delves into a global perspective on the challenges and opportunities in the understanding of MetALD.
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