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Updated: May 19, 2026

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Short-Term Visual and Optical Performance of the ZEISS CT LUCIA 621P Intraocular Lens Across Different Power Ranges.

Jiwon Jeong1,2, Younghee Kim2, Dong Wook Kim3

  • 1Fatima Eye Clinic, Changwon, Republic of Korea.

Clinical Ophthalmology (Auckland, N.Z.)
|May 18, 2026
PubMed
Summary

The ZEISS CT LUCIA 621P intraocular lens (IOL) provides excellent refractive predictability and visual performance across various implanted powers. This study confirms its reliable use in cataract surgery for consistent optical quality.

Keywords:
CT LUCIA 621PZEISS opticcataract surgerydiopter-stratified analysisnon-constant aspheric IOLoptical qualityvisual performance

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optical Science

Background:

  • Cataract surgery requires precise intraocular lens (IOL) power selection for optimal visual outcomes.
  • The ZEISS CT LUCIA 621P IOL features a non-constant aspheric design aimed at enhancing optical performance.
  • Evaluating IOL performance across a range of diopter powers is crucial for clinical application.

Purpose of the Study:

  • To assess the short-term efficacy and optical performance of the ZEISS CT LUCIA 621P IOL.
  • To evaluate performance stratified by implanted diopter (D) power.
  • To analyze visual acuity, refractive predictability, and optical quality metrics.

Main Methods:

  • Retrospective study of 304 eyes (216 patients) implanted with CT LUCIA 621P IOL.
  • Eyes stratified into four groups based on implanted IOL power (<20.0 D, 20.0-21.5 D, 22.0-23.5 D, ≥24.0 D).
  • Primary outcomes included defocus curves and higher-order aberrations; secondary outcomes included visual acuities and contrast sensitivity.

Main Results:

  • Excellent refractive predictability (SE convergence to emmetropia) observed across all IOL power groups (p=0.398).
  • Comparable monocular and binocular visual acuities (distance, intermediate, near) and contrast sensitivity across groups.
  • Consistent depth of focus and low postoperative aberrations (spherical aberration, coma) were noted.

Conclusions:

  • The ZEISS CT LUCIA 621P IOL demonstrates consistent refractive predictability and visual performance across a wide range of implanted powers.
  • The IOL provides reliable optical quality, supporting its use in modern cataract surgery.
  • The diopter-stratified approach confirmed consistent efficacy and optical performance regardless of IOL power.