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Csp3-H Bond Carbynoid Functionalization by Photoredox Catalysis
Lixing Shen1, Shaoyong Chen1, Jun Peng1
1Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, China.
None:
A photoredox-catalyzed Csp3-H carbynoid functionalization of 1,3-dicarbonyl compounds with α-iodionium diazo compounds has been developed to rapidly assemble α,β-diacyl-α,β-unsaturated ketones. This protocol offers a straightforward approach to access β-deuterated-α,β-unsaturated carbonyl molecules via a 1,2-H shift process.
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