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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
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Published on: March 20, 2014

Palladium-Catalyzed Three-Component Coupling Through Carbene Migratory Insertion: Access to Allenes and 1,5-Enynes

Xiao-Dong Liu1,2, Rui Tao3, Yuan-Ze Xu3

  • 1Department of Chemistry, The University of Hong Kong, Hong Kong, P. R. China.

Angewandte Chemie (International Ed. in English)
|May 18, 2026
PubMed
Summary

This study introduces a novel palladium-catalyzed three-component coupling reaction for synthesizing allenes and 1,5-enynes. The method efficiently combines bromoalkynes, diazoesters, and boronates, offering a versatile route to complex organic molecules.

Keywords:
allenylationcarbenemigratory insertionpalladium‐catalysispropargylationthree‐component reaction

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