Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Which Factors Are Associated With Death, Local Recurrence, and Perioperative Complications After En Bloc Resection for Primary Malignant Tumors of the Mobile Spine?

Clinical orthopaedics and related research·2026
Same author

Association of baseline HBcAg and HBV DNA with persistent detectability of HBV RNA during NA therapy.

PloS one·2026
Same author

Reactive machine-learned potentials for fluoropolymer binders: unified physical and chemical property validation.

Physical chemistry chemical physics : PCCP·2026
Same author

Predictive value of gut metabolites combined with neutrophil to platelet ratio for clinical functional outcome in acute ischemic stroke treated with endovascular therapy.

Frontiers in nutrition·2026
Same author

Olanzapine vs Low-Dose Dexmedetomidine for Delirium in Patients with Critical Illness: A Double-Blind Randomized Clinical Trial.

American journal of respiratory and critical care medicine·2026
Same author

Improved clinical efficacy of melasma with combination therapy of intense pulsed light and tranexamic acid: A retrospective analysis.

Medicine·2026
Same journal

Visual detection of uric acid and antibacterial applications in gout wound healing based on His@Fe-SHMP nanozyme.

Biosensors & bioelectronics·2026
Same journal

Multiplexed miRNA imaging using spherical nucleic acids and catalytic hairpin assembly for screening the differential immunotoxicity of deoxynivalenol and its acetylated derivatives in RAW264.7 cells.

Biosensors & bioelectronics·2026
Same journal

Circular RNA targeted theranostic nanoplatform for liver cancer-related gene detection and metastasis regulation in zebrafish using optical sensing and imaging.

Biosensors & bioelectronics·2026
Same journal

Robust and reusable iridium oxide-modified FTO electrodes for long-term organ-on-a-chip monitoring.

Biosensors & bioelectronics·2026
Same journal

Propylene carbonate-PVDF-HFP/MXene-based self-powered biosensor for auxiliary detection of salivary exosomal miRNA-155 in pediatric asthma.

Biosensors & bioelectronics·2026
Same journal

Nanostructured zinc-coordination supraparticles on cellulose fibers: A 3D-Printed μ-FAD integrated smartphone platform for multiplexed salivary metabolic monitoring.

Biosensors & bioelectronics·2026
See all related articles

Related Experiment Video

Updated: May 20, 2026

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
07:51

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

Published on: February 1, 2022

Graphene field-effect transistor microarray with simple preparation method, good stability, and high sensitivity for

Zhuoran Feng1, Chuntao Zhou1, Yiwen Wang1

  • 1School of Chemistry, Dalian University of Technology, Dalian, China.

Biosensors & Bioelectronics
|May 18, 2026
PubMed
Summary
This summary is machine-generated.

A novel, cost-effective graphene field-effect transistor (GFET) microarray offers high sensitivity for bioassays. This stable, flexible biosensor platform achieves femtomolar detection limits for biomarkers in patient serum.

Keywords:
Good stability in aqueous systemsGraphene field-effect transistor microarrayGraphene oxide/reduced graphene oxide heterostructureHigh sensitivityPreparation strategy

More Related Videos

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing
10:45

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing

Published on: August 29, 2025

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology
09:39

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

Related Experiment Videos

Last Updated: May 20, 2026

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
07:51

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

Published on: February 1, 2022

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing
10:45

Fabrication of a Solution-gated Indium-Tin-Oxide-based One-piece Transistor Enabling Sensitive Biosensing

Published on: August 29, 2025

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology
09:39

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biosensors

Background:

  • Graphene field-effect transistors (GFETs) show promise for bioassays but face challenges in cost, fabrication, and aqueous stability.
  • Existing GFET microarrays often suffer from poor performance in biological samples and complex manufacturing processes.

Purpose of the Study:

  • To develop a simple, cost-effective fabrication method for a highly stable and sensitive 8-channel GFET microarray on a flexible substrate.
  • To improve the analytical performance of GFETs in aqueous systems for practical bioassay applications.

Main Methods:

  • Fabrication involved drop-casting, vapor chemical reduction, low-temperature heat treatment, and oxygen plasma treatment on a polyethylene terephthalate substrate.
  • Created graphene oxide/reduced graphene oxide heterostructure channels with high conductivity and carboxyl groups for enhanced probe immobilization.
  • Tested stability in aqueous systems for 32 days and recyclability under thermal cycling.

Main Results:

  • The 8-channel GFET microarray demonstrated excellent electrical stability in aqueous solutions for up to 32 days and good recyclability.
  • Achieved femtomolar (fM) detection limits for interleukin-6 and DNA due to enhanced probe density.
  • Successfully quantified interleukin-6 in complex septic patient serum, validating its clinical diagnostic potential.

Conclusions:

  • The developed fabrication strategy offers a simple, scalable, and cost-effective approach for producing high-performance GFET microarrays.
  • This flexible GFET microarray exhibits significant potential for practical applications in sensitive bioassays, clinical diagnosis, and health surveillance.